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CD11c antibody

Anti-CD11c antibody used in IHC (Paraffin sections) (IHC-P). GTX04686
Anti-CD11c antibody used in Western Blot (WB). GTX04686

Cat. No. GTX04686

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P, ELISA

Reactivity

 Human, Mouse
Package
100 μg ($469)
See all CD11c products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 0.1-0.5 μg/mL
IHC-P 0.5-1 μg/mL
ELISA 0.1-0.5 μg/mL
Not tested in other applications.

Calculated MW

128 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na₂HPO₄

Preservative

No preservatives

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.5 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

E. coli-derived human CD11c recombinant protein (Position: S161-T342).

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

integrin subunit alpha X , CD11C , SLEB6

Cellular Localization

Membrane; Single-pass type I membrane protein

Background

This gene encodes the integrin alpha X chain protein. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as inactivated-C3b (iC3b) receptor 4 (CR4). The alpha X beta 2 complex seems to overlap the properties of the alpha M beta 2 integrin in the adherence of neutrophils and monocytes to stimulated endothelium cells, and in the phagocytosis of complement coated particles. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2013]

Database

Research Area

DATA IMAGES

Anti-CD11c antibody used in IHC (Paraffin sections) (IHC-P). GTX04686

GTX04686 IHC-P Image

IHC-P analysis of human tonsil tissue using GTX04686 CD11c antibody.
Antigen retrieval : Heat mediated citrate buffer (pH 6.0)
Dilution : 1 μg/mL

Anti-CD11c antibody used in Western Blot (WB). GTX04686

GTX04686 WB Image

WB analysis of various samples using GTX04686 CD11c antibody.
Lane 1 : Mouse spleen tissue lysate
Lane 2 : Mouse thymus tissue lysate
Loading : 50 μg
Dilution : 0.5 μg/mL

REFERENCE

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REVIEW

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Package List Price ($)
$ 469