GeneTex
United States (US)

CD11c antibody

GTX102519_WB_19011506_165.jpg

Cat No. GTX102519

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB
Reactivity Human
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500-1:3000
Not tested in other applications.

Calculated MW

128 kDa. ( Note )

Positive Control

H1299 , HeLaS3 , HepG2 , Raji
PROPERTIES

Form

Liquid

Buffer

0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1mg/ml

Antigen Species

Human

Immunogen

Recombinant protein encompassing a sequence within the N-terminus region of human Integrin alphaX. The exact sequence is proprietary.

Purification

Purified by antigen-affinity chromatography.

Conjugation

Unconjugated

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

CD11C antibody, SLEB6 antibody, ITGAX antibody, "integrin, alpha X (antigen CD11C (p150), alpha polypeptide) antibody", p150 95 integrin alpha chain antibody, "leukocyte surface antigen p150,95, alpha subunit antibody", "leukocyte adhesion glycoprotein p150,95 alpha chain antibody", "leukocyte adhesion receptor p150,95 antibody", "myeloid membrane antigen, alpha subunit antibody", integrin alpha-X antibody, "leu M5, alpha subunit antibody", CD11 antigen-like family member C antibody, "integrin, alpha X (complement component 3 receptor 4 subunit) antibody"

Cellular Localization

Membrane; Single-pass type I membrane protein

Background

This gene encodes the integrin alpha X chain protein. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as inactivated-C3b (iC3b) receptor 4 (CR4). The alpha X beta 2 complex seems to overlap the properties of the alpha M beta 2 integrin in the adherence of neutrophils and monocytes to stimulated endothelium cells, and in the phagocytosis of complement coated particles. [provided by RefSeq]
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Database

Research Area

DATA IMAGES
GTX102519_WB_19011506_165.jpg

GTX102519 WB Image

Sample(30 ug whole cell lysate)
A:H1299
B:Hep G2 (GTX27900)
7.5% SDS PAGE
GTX102519 diluted at 1:1000

SDS
Glycerol.pdf
Thimerosal.pdf