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CD11c antibody

Anti-CD11c antibody used in IHC (Paraffin sections) (IHC-P). GTX54062

Cat. No. GTX54062

Reference 1

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 IHC-P

Reactivity

 Human
Package
50 μg ($469)
See all CD11c products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-P 5 - 10 μg/ml

Note :

IHC-P
Heat induced antigen retrieval in pH 6.0 citrate buffer
Not tested in other applications.

Calculated MW

128 kDa. ( Note )

Predict Reactivity

Gibbon, Gorilla, Marmoset(>80% identity)

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.1% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Synthetic 15 amino acid peptide from internal region of human CD11c.

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

RRID

AB_2887839

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

integrin subunit alpha X , CD11C , ITGAX , SLEB6 , CD11c , Integrin alpha X

Cellular Localization

Membrane

Background

This gene encodes the integrin alpha X chain protein. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as inactivated-C3b (iC3b) receptor 4 (CR4). The alpha X beta 2 complex seems to overlap the properties of the alpha M beta 2 integrin in the adherence of neutrophils and monocytes to stimulated endothelium cells, and in the phagocytosis of complement coated particles. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2013]

Database

Research Area

DATA IMAGES

Anti-CD11c antibody used in IHC (Paraffin sections) (IHC-P). GTX54062

GTX54062 IHC-P Image

IHC-P analysis of human prostate tissue using GTX54062 CD11c antibody.
Antigen retrieval : Heat-induced antigen retrieval
Dilution : 5-10μg/ml

REFERENCE

Application Reference

Nagai T et al. J Am Heart Assoc 2014; 3 (3) : e000839 Decreased myocardial dendritic cells is associated with impaired reparative fibrosis and development of cardiac rupture after myocardial infarction in humans.
Application : IHC-P
Reactivity : Human
Submit a Reference

REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 469