APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
| Application |
Recommended Dilution |
| 1:80 |
|
Note :
IHC-P
The recommended fixative is 10% neutral-buffered formalin for paraffin-embedded tissue sections. Heat Induced Epitope Retreival (HIER) was performed in Epitope Retreival Solution pH6.
|
Not tested in other applications.
Calculated MW
PROPERTIES
Form
Liquid
Buffer
Tissue culture supernatant
Preservative
0.09% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.
Antigen Species
Human
Immunogen
Recombinant prokaryotic fusion protein corresponding to the C-terminal region of the extracellular domain.
Purification
Unpurified
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
alanyl aminopeptidase, membrane , APN , CD13 , GP150 , LAP1 , P150 , PEPN
Cellular Localization
Cell membrane
Background
Aminopeptidase N is located in the small-intestinal and renal microvillar membrane, and also in other plasma membranes. In the small intestine aminopeptidase N plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. Its function in proximal tubular epithelial cells and other cell types is less clear. The large extracellular carboxyterminal domain contains a pentapeptide consensus sequence characteristic of members of the zinc-binding metalloproteinase superfamily. Sequence comparisons with known enzymes of this class showed that CD13 and aminopeptidase N are identical. The latter enzyme was thought to be involved in the metabolism of regulatory peptides by diverse cell types, including small intestinal and renal tubular epithelial cells, macrophages, granulocytes, and synaptic membranes from the CNS. Human aminopeptidase N is a receptor for one strain of human coronavirus that is an important cause of upper respiratory tract infections. Defects in this gene appear to be a cause of various types of leukemia or lymphoma. [provided by RefSeq, Jul 2008]
Database
Research Area
DATA IMAGES
![Anti-CD13 antibody [38C12] used in IHC (Paraffin sections) (IHC-P). GTX01910](/templates/default/js/lightbox/images/loading.gif "Anti-CD13 antibody [38C12] used in IHC (Paraffin sections) (IHC-P). GTX01910")
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GTX01910 IHC-P Image
IHC-P analysis of human liver tissue using GTX01910 CD13 antibody [38C12]. Note staining of the bile canaliculi.
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REFERENCE
There are currently no references for CD13 antibody [38C12] (GTX01910). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for CD13 antibody [38C12] (GTX01910). Be the first to share your experience with this product.
![Anti-CD13 antibody [38C12] used in IHC (Paraffin sections) (IHC-P). GTX01910](/upload/website/prouct_img/small/GTX01910/GTX01910_20200811_IHC-P_12_w_23053121_581.webp "Anti-CD13 antibody [38C12] used in IHC (Paraffin sections) (IHC-P). GTX01910")
![Anti-CD13 antibody [38C12] used in IHC (Paraffin sections) (IHC-P). GTX01910](/upload/website/prouct_img/normal/GTX01910/GTX01910_20200811_IHC-P_12_w_23053121_581.webp "Anti-CD13 antibody [38C12] used in IHC (Paraffin sections) (IHC-P). GTX01910")