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CD13 antibody [WM15] (FITC)

Anti-CD13 antibody [WM15] (FITC) used in Flow cytometry (FACS). GTX74833

Cat. No. GTX74833

Reference 2

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 WM15

Isotype

 IgG1

Application

 FACS

Reactivity

 Human, Rabbit, Primate
Package
100 μg ($339)
See all CD13 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
FACS 20 μl reagent / 100 μl of whole blood or 10⁶ cells in a suspension
Not tested in other applications.

Calculated MW

110 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

15mM Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE. Protect from light.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Human AML cells

Purification

Purified by size-exclusion chromatography

Conjugation

Fluorescein isothiocyanate (FITC)

RRID

AB_376490

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

ANPEP , APN , CD13 , GP150 , LAP1 , P150 , PEPN , alanyl aminopeptidase, membrane

Cellular Localization

Cell membrane

Background

Aminopeptidase N is located in the small-intestinal and renal microvillar membrane, and also in other plasma membranes. In the small intestine aminopeptidase N plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. Its function in proximal tubular epithelial cells and other cell types is less clear. The large extracellular carboxyterminal domain contains a pentapeptide consensus sequence characteristic of members of the zinc-binding metalloproteinase superfamily. Sequence comparisons with known enzymes of this class showed that CD13 and aminopeptidase N are identical. The latter enzyme was thought to be involved in the metabolism of regulatory peptides by diverse cell types, including small intestinal and renal tubular epithelial cells, macrophages, granulocytes, and synaptic membranes from the CNS. Human aminopeptidase N is a receptor for one strain of human coronavirus that is an important cause of upper respiratory tract infections. Defects in this gene appear to be a cause of various types of leukemia or lymphoma. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-CD13 antibody [WM15] (FITC) used in Flow cytometry (FACS). GTX74833

GTX74833 FACS Image

FACS analysis of human peripheral blood leukocytes using GTX74833 CD13 antibody [WM15] (FITC).

REFERENCE

Application Reference

Lee TC et al. PLoS One 2014; 9 (11) : e111390 Comparison of Surface Markers between Human and Rabbit Mesenchymal Stem Cells.
Application : FACS
Reactivity : Human, Rabbit

Clone Reference

Haraguchi N et al. J Clin Invest 2010; 120 (9):3326-39 CD13 is a therapeutic target in human liver cancer stem cells.
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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 339