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CD133 antibody [293C3] (APC)

Anti-CD133 antibody [293C3] (APC) used in Flow cytometry (FACS). GTX00508-07

Cat No. GTX00508-07

Host

Mouse

Clonality

Monoclonal

Clone Name

293C3

Isotype

IgG2b

Application

FACS

Reactivity

Human
Package
100 test ($329)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
FACS 10 μl reagent / 100 μl of whole blood or 10⁶ cells in a suspension
Not tested in other applications.

Specificity/Sensitivity

This antibody recognizes the epitope 2 on human CD133 (CD133/2), a 120 kDa glycoprotein of prominin family, expressed e.g. on progenitor cells. This antibody is important for identification of human renal progenitors.

PROPERTIES

Form

Liquid

Buffer

PBS, 15mM sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE. Protect from light.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Purification

Purified by size-exclusion chromatography

Conjugation

Allophycocyanin (APC)

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

AC133 , CD133 , CORD12 , MCDR2 , MSTP061 , PROM1 , PROML1 , RP41 , STGD4 , prominin 1

Cellular Localization

Apical cell membrane,Cell projection,Microvillus membrane,Cilium,Photoreceptor outer segment,Endoplasmic reticulum,Endoplasmic reticulum-Golgi intermediate compartment,Cell projection (by similarity),Cilium (by similarity),Photoreceptor outer segment (by similarity)

Background

This gene encodes a pentaspan transmembrane glycoprotein. The protein localizes to membrane protrusions and is often expressed on adult stem cells, where it is thought to function in maintaining stem cell properties by suppressing differentiation. Mutations in this gene have been shown to result in retinitis pigmentosa and Stargardt disease. Expression of this gene is also associated with several types of cancer. This gene is expressed from at least five alternative promoters that are expressed in a tissue-dependent manner. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]

Database

Research Area

DATA IMAGES

Anti-CD133 antibody [293C3] (APC) used in Flow cytometry (FACS). GTX00508-07

GTX00508-07 FACS Image

FACS analysis of human peripheral blood using GTX00508-07 CD133 antibody [293C3] (APC).

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 329