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CD133 antibody [W6B3C1] (PE)

Cat. No. GTX00509-08

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 W6B3C1

Isotype

 IgG1

Application

 FACS

Reactivity

 Human
Package
100 test ($359)
See all CD133 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
FACS 10 μl reagent / 100 μl of whole blood or 10⁶ cells in a suspension
Not tested in other applications.

Product Note

This antibody recognizes a glycosylated epitope 1 on human CD133 (CD133/1), a 120 kDa glycoprotein of prominin family, expressed e.g. on progenitor cells. This antibody is important for identification of stem cells and tumor cells.

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

15mM Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE. Protect from light.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

WERI-RB-1 retinoblastoma cell line

Purification

Purified by size-exclusion chromatography

Conjugation

Phycoerythrin (PE) Wavelength

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

AC133 , CD133 , CORD12 , MCDR2 , MSTP061 , PROM1 , PROML1 , RP41 , STGD4 , prominin 1

Cellular Localization

Apical cell membrane,Cell projection,Microvillus membrane,Cilium,Photoreceptor outer segment,Endoplasmic reticulum,Endoplasmic reticulum-Golgi intermediate compartment,Cell projection (by similarity),Cilium (by similarity),Photoreceptor outer segment (by similarity)

Background

This gene encodes a pentaspan transmembrane glycoprotein. The protein localizes to membrane protrusions and is often expressed on adult stem cells, where it is thought to function in maintaining stem cell properties by suppressing differentiation. Mutations in this gene have been shown to result in retinitis pigmentosa and Stargardt disease. Expression of this gene is also associated with several types of cancer. This gene is expressed from at least five alternative promoters that are expressed in a tissue-dependent manner. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]

Database

Research Area

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 359