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CD133 antibody [W6B3C1]

Anti-CD133 antibody [W6B3C1] used in Flow cytometry (FACS). GTX00509

Cat No. GTX00509

Host

Mouse

Clonality

Monoclonal

Clone Name

W6B3C1

Isotype

IgG1

Application

WB, FACS, IHC

Reactivity

Human
Package
100 μg ($319)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB Assay dependent
FACS Assay dependent
IHC Assay dependent
Not tested in other applications.

Specificity/Sensitivity

This antibody recognizes a glycosylated epitope 1 on human CD133 (CD133/1), a 120 kDa glycoprotein of prominin family, expressed e.g. on progenitor cells. This antibody is important for identification of stem cells and tumor cells.

PROPERTIES

Form

Liquid

Buffer

PBS, 15mM sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

WERI-RB-1 retinoblastoma cell line

Purification

Protein A purified
From tissue culture supernatant

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

AC133,CD133,CORD12,MCDR2,MSTP061,PROM1,PROML1,RP41,STGD4,prominin 1

Cellular Localization

Apical cell membrane,Cell projection,Microvillus membrane,Cilium,Photoreceptor outer segment,Endoplasmic reticulum,Endoplasmic reticulum-Golgi intermediate compartment,Cell projection (by similarity),Cilium (by similarity),Photoreceptor outer segment (by similarity)

Background

This gene encodes a pentaspan transmembrane glycoprotein. The protein localizes to membrane protrusions and is often expressed on adult stem cells, where it is thought to function in maintaining stem cell properties by suppressing differentiation. Mutations in this gene have been shown to result in retinitis pigmentosa and Stargardt disease. Expression of this gene is also associated with several types of cancer. This gene is expressed from at least five alternative promoters that are expressed in a tissue-dependent manner. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]

Database

Research Area

DATA IMAGES

Anti-CD133 antibody [W6B3C1] used in Flow cytometry (FACS). GTX00509

GTX00509 FACS Image

FACS analysis of human peripheral blood using GTX00509 CD133 antibody [W6B3C1].

REFERENCE

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REVIEW

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Package List Price ($)
$ 319