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CD14 antibody [18D11]

Cat. No. GTX54479

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 18D11

Isotype

 IgG1

Application

 FACS, ELISA, Functional Assay

Reactivity

 Human, Pig
Package
50 μg ($399)
See all CD14 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
FACS Assay dependent
ELISA Assay dependent
Functional Assay Assay dependent
Not tested in other applications.

Calculated MW

40 kDa. ( Note )

Product Note

The monoclonal antibody 18D11 reacts with both soluble and membrane CD14. The monoclonal antibody 18D11 is useful for inhibition of biological activity of sCD14, it inhibits LPS induced TNF production. Together with a C5a neutralizing monoclonal antibody, 18D11 blocks sepsis in a pig model.

PROPERTIES

Form

Liquid

Buffer

Filter-sterilized PBS, 0.1% BSA

Preservative

No preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.

Concentration

100 μg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Purification

Purified IgG1

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

CD14,CD14 molecule

Cellular Localization

Cell membrane

Background

The protein encoded by this gene is a surface antigen that is preferentially expressed on monocytes/macrophages. It cooperates with other proteins to mediate the innate immune response to bacterial lipopolysaccharide. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Mar 2010]

Database

Research Area

REFERENCE

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REVIEW

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Package List Price ($)
$ 399