GeneTex
United States (US)

CD14 antibody [CRIS-6] (PE)

Cat No. GTX16175

Host Mouse
Clonality Monoclonal
Clone Name CRIS-6
Isotype IgG1
Application ICC/IF, FACS, IP
Reactivity Human
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
ICC/IF Assay dependent
FACS Assay dependent
IP Assay dependent
Not tested in other applications.

Calculated MW

40 kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

Preservative: 0.1% Sodium Azide; Constituents: PBS, 1mg/ml BSA

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. Protect from light.

Antigen Species

Human

Immunogen

Tissue / cell preparation (Human peripheral blood mononuclear cells).

Purification

Protein G purified

Conjugation

Phycoerythrin (PE)

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Cd14 Molecule,Cd14

Cellular Localization

Cytoplasmic. Attached to the membrane by a GPI anchor.

Background

CD14 is a single-copy gene encoding 2 protein forms: a 50- to 55-kD glycosylphosphatidylinositol-anchored membrane protein (mCD14) and a monocyte or liver-derived soluble serum protein (sCD14) that lacks the anchor. Both molecules are critical for lipopolysaccharide (LPS)-dependent signal transduction, and sCD14 confers LPS sensitivity to cells lacking mCD14. Increased sCD14 levels are associated with inflammatory infectious diseases and high mortality in gram-negative shock.

Database

Research Area

Package List Price ($)
$ 319