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CD146 antibody [MUC18/1130]

Anti-CD146 antibody [MUC18/1130] used in IHC (Paraffin sections) (IHC-P). GTX34461
Anti-CD146 antibody [MUC18/1130] used in IHC (Paraffin sections) (IHC-P). GTX34461
Anti-CD146 antibody [MUC18/1130] used in IHC (Paraffin sections) (IHC-P). GTX34461

Cat No. GTX34461

Host

Mouse

Clonality

Monoclonal

Clone Name

MUC18/1130

Isotype

IgG1

Application

ICC/IF, IHC-P

Reactivity

Human
Package
100 μg ($429)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
ICC/IF 0.5-1.0ug/ml
IHC-P 0.5-1ug/ml for 30 minutes at RT

Note :

IHC-P
Boiling tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 10-20 min followed by cooling at RT for 20 minutes

Not tested in other applications.

Calculated MW

72 kDa. ( Note )

Specificity/Sensitivity

The human Mel-CAM gene maps to chromosome 11q23 and encodes a trans-membrane glycoprotein, also designated MCAM, MUC 18 or CD146, that belongs to the immunoglobulin superfamily and functions as a Ca2+-independent cell adhesion molecule. Mel-CAM expression is restricted to advanced primary and metastatic melanomas and to cell lines of the neuroectodermal lineage, but not normal melanocytes. Mel-CAM is found on 80% of advanced primary human melanomas and correlates well with development of metastatic disease.

PROPERTIES

Form

Liquid

Buffer

10mM PBS with 0.05% BSA, 0.05% azide (Please contact us for PBS only format)

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.2 mg/ml

Antigen Species

Human

Immunogen

Recombinant human MUC18 protein

Purification

Ab purified from Bioreactor Concentrate by Protein A/G

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

Melanoma Cell Adhesion Molecule , Cd146 , Hemcam , Metcam , Muc18 , Melcam , Mcam

Database

Research Area

DATA IMAGES

Anti-CD146 antibody [MUC18/1130] used in IHC (Paraffin sections) (IHC-P). GTX34461

GTX34461 IHC-P Image

Formalin-fixed, paraffin-embedded human Melanoma stained with MUC18 Monoclonal Antibody (MUC18/1130)

Anti-CD146 antibody [MUC18/1130] used in IHC (Paraffin sections) (IHC-P). GTX34461

GTX34461 IHC-P Image

Formalin-fixed, paraffin-embedded human Melanoma stained with MUC18 Monoclonal Antibody (MUC18/1130)

Anti-CD146 antibody [MUC18/1130] used in IHC (Paraffin sections) (IHC-P). GTX34461

GTX34461 IHC-P Image

Formalin-fixed, paraffin-embedded human Tonsil stained with MUC18 Monoclonal Antibody (MUC18/1130)

REFERENCE

There are currently no references for CD146 antibody [MUC18/1130] (GTX34461). Be the first to share your publications with this product.

REVIEW

There are currently no reviews for CD146 antibody [MUC18/1130] (GTX34461). Be the first to share your experience with this product.
Package List Price ($)
$ 429