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CD147 antibody [BSG/963]

Anti-CD147 antibody [BSG/963] used in IHC (Paraffin sections) (IHC-P). GTX34463
Anti-CD147 antibody [BSG/963] used in IHC (Paraffin sections) (IHC-P). GTX34463
Anti-CD147 antibody [BSG/963] used in IHC (Paraffin sections) (IHC-P). GTX34463

Cat No. GTX34463

Host Mouse
Clonality Monoclonal
Clone Name BSG/963
Isotype IgG1
Application ICC/IF, IHC-P
Reactivity Human
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
ICC/IF 1:100-1:200
IHC-P 0.5-1ug/ml for 30 minutes at RT

Note :

IHC-P
Boiling tissue sections in 10mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes

Not tested in other applications.

Calculated MW

42 kDa. ( Note )

Specificity/Sensitivity

This MAb recognizes extracellular epitope of human CD147. It is expressed more intensely on thymocytes than on mature peripheral blood T cells. CD147 is important in spermatogenesis, embryo implantation, neural network formation, and tumor progression. It stimulates the production of interstitial collagenase, gelatinase A, stromelysin-1 and various metalloproteinases (MMPs) by fibroblasts. These enzymes are important factors in cancer invasion and metastasis.
PROPERTIES

Form

Liquid

Buffer

Prepared in 10mM PBS with 0.05% BSA and 0.05% azide.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Recombinant human BSG protein

Purification

Ab purified from Bioreactor Concentrate by Protein A/G

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Basigin (Ok Blood Group),5F7,Cd147,Emmprin,Emprin,Ok,Tcsf,Bsg

Background

The protein encoded by this gene is a plasma membrane protein that is important in spermatogenesis, embryo implantation, neural network formation, and tumor progression. The encoded protein is also a member of the immunoglobulin superfamily. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES
Anti-CD147 antibody [BSG/963] used in IHC (Paraffin sections) (IHC-P). GTX34463

GTX34463 IHC-P Image

Formalin-fixed, paraffin-embedded human Testicular Carcinoma stained with CD147 Monoclonal Antibody (BSG/963).

Anti-CD147 antibody [BSG/963] used in IHC (Paraffin sections) (IHC-P). GTX34463

GTX34463 IHC-P Image

Formalin-fixed, paraffin-embedded human Renal Cell Carcinoma stained with CD147 Monoclonal Antibody (BSG/963).

Anti-CD147 antibody [BSG/963] used in IHC (Paraffin sections) (IHC-P). GTX34463

GTX34463 IHC-P Image

Formalin-fixed, paraffin-embedded human Colon Carcinoma stained with CD147 Monoclonal Antibody (BSG/963).

Package List Price ($)
$ 329