GeneTex
United States (US)

CD147 antibody

Cat No. GTX11572

Host Goat
Clonality Polyclonal
Isotype IgG
Application WB
Reactivity Human
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 0.1-0.2 μg/ml
Not tested in other applications.

Calculated MW

42 kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

PBS, 5% trehalose

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

purified recombinant human extracellular matrix metalloproteinase inducer extracellular domain, expressed in NSO cells.

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Basigin (Ok Blood Group),5F7,Cd147,Emmprin,Emprin,Ok,Tcsf,Bsg

Background

EMMPRIN (extracellular matrix metalloproteinase inducer), also called CD147, basigin, and M6 in humans, is a member of the immunoglobulin superfamily. It is a glycoprotein containing two immunogbulin domains. EMMPRIN is present on the surface of tumor cells and macrophages and stimulates fibroblasts to produce matrix metalloproteinases (MMPs). The expression of EMMPRIN is different from that in normal human brain. Human keratinocytes express EMMPRIN suggesting the possibility of its involvement in the regulation of matrix remodeling at the epidermal-dermal junction.

Database

Research Area

Package List Price ($)
$ 319