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United States (US)

CD147 antibody

Cat. No. GTX11572

Host

 Goat

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB

Reactivity

 Human
Package
25 μg ($399)
See all CD147 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 0.1-0.2 μg/ml
Not tested in other applications.

Calculated MW

42 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 5% Trehalose

Preservative

No preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

purified recombinant human extracellular matrix metalloproteinase inducer extracellular domain, expressed in NSO cells.

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

basigin (Ok blood group) , 5F7 , CD147 , EMMPRIN , EMPRIN , OK , SLC7A11 , TCSF

Cellular Localization

Cell membrane

Background

EMMPRIN (extracellular matrix metalloproteinase inducer), also called CD147, basigin, and M6 in humans, is a member of the immunoglobulin superfamily. It is a glycoprotein containing two immunogbulin domains. EMMPRIN is present on the surface of tumor cells and macrophages and stimulates fibroblasts to produce matrix metalloproteinases (MMPs). The expression of EMMPRIN is different from that in normal human brain. Human keratinocytes express EMMPRIN suggesting the possibility of its involvement in the regulation of matrix remodeling at the epidermal-dermal junction.

Database

Research Area

REFERENCE

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REVIEW

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SDS
PBS.pdf
Package List Price ($)
$ 399