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CD153 antibody [3G56]

Cat No. GTX52621

Host

Mouse

Clonality

Monoclonal

Clone Name

3G56

Isotype

IgG2

Application

WB

Reactivity

Human
Package
100 μg ($329)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500 - 1:1000
Not tested in other applications.

Calculated MW

26 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

500 μg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Human recombinant TNFSF8 EC domain

Purification

Protein G purified
From tissue culture supernatant

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

CD153 , CD30L , CD30LG , TNFSF8 , TNLG3A , tumor necrosis factor superfamily member 8 , CD30 Ligand , TNF superfamily member 8

Cellular Localization

Membrane

Background

The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF8/CD30, which is a cell surface antigen and a marker for Hodgkin lymphoma and related hematologic malignancies. The engagement of this cytokine expressed on B cell surface plays an inhibitory role in modulating Ig class switch. This cytokine was shown to enhance cell proliferation of some lymphoma cell lines, while to induce cell death and reduce cell proliferation of other lymphoma cell lines. The pleiotropic biologic activities of this cytokine on different CD30+ lymphoma cell lines may play a pathophysiologic role in Hodgkin's and some non-Hodgkin's lymphomas. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]

Database

Research Area

REFERENCE

There are currently no references for CD153 antibody [3G56] (GTX52621). Be the first to share your publications with this product.

REVIEW

There are currently no reviews for CD153 antibody [3G56] (GTX52621). Be the first to share your experience with this product.
SDS
PBS.pdf
Package List Price ($)
$ 329