APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
| Application |
Recommended Dilution |
| neat-1:10 |
|
Note :
FACS
Use 100μl of the suggested working dilution to label 1x 10⁶ cells in 100μl.
|
Not tested in other applications.
Calculated MW
Product Note
Clone KD1 recognizes both forms of CD16 and will therefore recognize all cell types expressing CD16.
We do not recommend use of this product for Rat,Dog samples.
PROPERTIES
Form
Liquid
Buffer
PBS, 1% BSA
Preservative
0.09% Sodium Azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. Protect from light.
Concentration
0.1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
A polyclonal population of NK cells.
Purification
Purified by affinity chromatography
From tissue culture supernatant
Conjugation
Fluorescein isothiocyanate (FITC)
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
Fc fragment of IgG receptor IIIa , Fc fragment of IgG receptor IIIb , CD16 , CD16A , FCG3 , FCGR3 , FCGRIII , FCR-10 , FCRIII , FCRIIIA , IGFR3 , IMD20 , CD16 , CD16A , CD16b , FCG3 , FCGR3 , FCGR3A , FCR-10 , FCRIII , FCRIIIb
Cellular Localization
Cell membrane,Secreted
Background
This gene encodes a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody complexes from the circulation, as well as other other antibody-dependent responses. This gene (FCGR3A) is highly similar to another nearby gene (FCGR3B) located on chromosome 1. The receptor encoded by this gene is expressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide, whereas FCGR3B is expressed on polymorphonuclear neutrophils (PMN) where the receptor is anchored through a phosphatidylinositol (PI) linkage. Mutations in this gene have been linked to susceptibility to recurrent viral infections, susceptibility to systemic lupus erythematosus, and alloimmune neonatal neutropenia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Database
Research Area
REFERENCE
There are currently no references for CD16 antibody [KD1] (FITC) (GTX04886-06). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for CD16 antibody [KD1] (FITC) (GTX04886-06). Be the first to share your experience with this product.
