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CD16 antibody [LNK16] (FITC)

Orthogonal
Anti-CD16 antibody [LNK16] (FITC) used in Flow cytometry (FACS). GTX74719
Anti-CD16 antibody [LNK16] (FITC) used in Flow cytometry (FACS). GTX74719
Anti-CD16 antibody [LNK16] (FITC) used in Flow cytometry (FACS). GTX74719

Cat. No. GTX74719

Reference 1

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 LNK16

Isotype

 IgG1

Application

 FACS

Reactivity

 Human, Primate
Package
100 test ($329)
See all CD16 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
FACS 20 μl reagent / 100 μl of whole blood or 10⁶ cells in a suspension
Not tested in other applications.

Calculated MW

29 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

15mM Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE. Protect from light.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Normal human peripheral blood granulocytes

Purification

Purified by size-exclusion chromatography

Conjugation

Fluorescein isothiocyanate (FITC)

RRID

AB_376435

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

CD16 , CD16A , FCG3 , FCGR3 , FCGR3A , FCGRIII , FCR10 , FCRIII , FCRIIIA , Fc fragment of IgG receptor IIIa , IGFR3 , IMD20 , CD16a

Cellular Localization

Cell membrane,Secreted

Background

This gene encodes a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody complexes from the circulation, as well as other other antibody-dependent responses. This gene (FCGR3A) is highly similar to another nearby gene (FCGR3B) located on chromosome 1. The receptor encoded by this gene is expressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide, whereas FCGR3B is expressed on polymorphonuclear neutrophils (PMN) where the receptor is anchored through a phosphatidylinositol (PI) linkage. Mutations in this gene have been linked to susceptibility to recurrent viral infections, susceptibility to systemic lupus erythematosus, and alloimmune neonatal neutropenia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-CD16 antibody [LNK16] (FITC) used in Flow cytometry (FACS). GTX74719

GTX74719 FACS Image

FACS analysis of human lymphocytes using GTX74719 CD16 antibody [LNK16] (FITC).
Antibody amount : 20 μl reagent / 100 μl of peripheral whole blood

Anti-CD16 antibody [LNK16] (FITC) used in Flow cytometry (FACS). GTX74719

GTX74719 FACS Image

FACS analysis of human peripheral blood using GTX74719 CD16 antibody [LNK16] (FITC).
Antibody amount : 20 μl reagent / 100 μl of peripheral whole blood

Anti-CD16 antibody [LNK16] (FITC) used in Flow cytometry (FACS). GTX74719

GTX74719 FACS Image

Orthogonal

FACS analysis of human CD3 negative CD16 positive Lymphocytes (red-filled) and human CD3 positive CD16 negative Lymphocytes (black-dashed) using GTX74719 CD16 antibody [LNK16] (FITC).
Antibody amount : 20 μl reagent / 100 μl of peripheral whole blood

REFERENCE

Clone Reference

Schulz U et al. Transfusion 2016; (Epub) Evaluation of a new microbeads assay for granulocyte antibody detection.
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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 329