GeneTex

  • Country / Location Selection

United States (US)

CD16 antibody [MEM-154]

Anti-CD16 antibody [MEM-154] used in Flow cytometry (FACS). GTX20664

Cat. No. GTX20664

Reference 1

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 MEM-154

Isotype

 IgG1

Application

 WB, FACS, IP

Reactivity

 Human
Package
100 μg ($399)
See all CD16 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB Assay dependent
FACS Assay dependent
IP Assay dependent
Not tested in other applications.

Calculated MW

29 kDa. ( Note )

Product Note

This antibody reacts with an epitope on CD16 antigen that is residing in proximity to FG loop (probably BC or C'E loop).

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

15mM Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Human granulocytes

Purification

Protein A purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

CD16 , CD16A , FCG3 , FCGR3 , FCGR3A , FCGRIII , FCR10 , FCRIII , FCRIIIA , Fc fragment of IgG receptor IIIa , IGFR3 , IMD20 , CD16a

Cellular Localization

Cell membrane,Secreted

Background

This gene encodes a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody complexes from the circulation, as well as other other antibody-dependent responses. This gene (FCGR3A) is highly similar to another nearby gene (FCGR3B) located on chromosome 1. The receptor encoded by this gene is expressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide, whereas FCGR3B is expressed on polymorphonuclear neutrophils (PMN) where the receptor is anchored through a phosphatidylinositol (PI) linkage. Mutations in this gene have been linked to susceptibility to recurrent viral infections, susceptibility to systemic lupus erythematosus, and alloimmune neonatal neutropenia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-CD16 antibody [MEM-154] used in Flow cytometry (FACS). GTX20664

GTX20664 FACS Image

Surface staining of human peripheral blood cells with anti-human CD16 (GTX20664): PE. The antibody MEM-154 does not react with CD16a present on NK cells in many subjects

REFERENCE

Clone Reference

Sun D et al. J Immunol 2012; 189 (5):2423-31 Anti-peptidoglycan antibodies and Fcγ receptors are the key mediators of inflammation in Gram-positive sepsis.
Application : FACS
Reactivity : Human
Submit a Reference

REVIEW

There are currently no reviews for CD16 antibody [MEM-154] (GTX20664). Be the first to share your experience with this product.
Submit a Review
SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399