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CD162 antibody [TC2] (PE)

Anti-CD162 antibody [TC2] (PE) used in Flow cytometry (FACS). GTX79886

Cat. No. GTX79886

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 TC2

Isotype

 IgG1

Application

 FACS

Reactivity

 Human
Package
100 test ($329)
See all CD162 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
FACS 20 μl reagent / 100 μl of whole blood or 10⁶ cells in a suspension
Not tested in other applications.

Calculated MW

43 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

15mM Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE. Protect from light.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Human thymocytes

Purification

Purified by size-exclusion chromatography

Conjugation

Phycoerythrin (PE)

RRID

AB_11179118

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

CD162 , CLA , PSGL1 , SELPLG , selectin P ligand , PSGL-1

Cellular Localization

Membrane

Background

This gene encodes a glycoprotein that functions as a high affinity counter-receptor for the cell adhesion molecules P-, E- and L- selectin expressed on myeloid cells and stimulated T lymphocytes. As such, this protein plays a critical role in leukocyte trafficking during inflammation by tethering of leukocytes to activated platelets or endothelia expressing selectins. This protein requires two post-translational modifications, tyrosine sulfation and the addition of the sialyl Lewis x tetrasaccharide (sLex) to its O-linked glycans, for its high-affinity binding activity. Aberrant expression of this gene and polymorphisms in this gene are associated with defects in the innate and adaptive immune response. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Apr 2011]

Database

Research Area

DATA IMAGES

Anti-CD162 antibody [TC2] (PE) used in Flow cytometry (FACS). GTX79886

GTX79886 FACS Image

Surface staining of human peripheral blood cells with anti-human CD162 (clone TC2).

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 329