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CD163 antibody [10D6]

Anti-CD163 antibody [10D6] used in IHC (Paraffin sections) (IHC-P). GTX04717

Cat. No. GTX04717

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 10D6

Isotype

 IgG1

Application

 IHC-P

Reactivity

 Human
Package
500 μl ($589)
See all CD163 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-P 1:25-1:100

Note :

IHC-P
Recommendations for antigen retrieval : Citrate Buffer pH 6.0 at room temperature for 30 mins.
Not tested in other applications.

PROPERTIES

Form

Liquid

Buffer

batch dependent

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Human CD163 antigen

Purification

Unpurified
From tissue culture supernatant

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

CD163,CD163 molecule,M130,MM130,SCARI1

Cellular Localization

Secreted,Cell membrane

Background

The protein encoded by this gene is a member of the scavenger receptor cysteine-rich (SRCR) superfamily, and is exclusively expressed in monocytes and macrophages. It functions as an acute phase-regulated receptor involved in the clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages, and may thereby protect tissues from free hemoglobin-mediated oxidative damage. This protein may also function as an innate immune sensor for bacteria and inducer of local inflammation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011]

Database

Research Area

DATA IMAGES

Anti-CD163 antibody [10D6] used in IHC (Paraffin sections) (IHC-P). GTX04717

GTX04717 IHC-P Image

IHC-P analysis of human tonsil tissue using GTX04717 CD163 antibody [10D6].
Antigen retrieval : Citrate Buffer pH 6.0_x000D_

REFERENCE

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REVIEW

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Package List Price ($)
$ 589