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CD163 antibody [M130/1210]

Anti-CD163 antibody [M130/1210] used in IHC (Paraffin sections) (IHC-P). GTX18027
Anti-CD163 antibody [M130/1210] used in IHC (Paraffin sections) (IHC-P). GTX18027
Anti-CD163 antibody [M130/1210] used in Western Blot (WB). GTX18027
Anti-CD163 antibody [M130/1210] used in Protein Array (Protein Array). GTX18027

Cat. No. GTX18027

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 M130/1210

Isotype

 IgG2b

Application

 WB, IHC-P, Protein Array

Reactivity

 Human
Package
100 μg ($529)
See all CD163 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1-2μg/ml
IHC-P 1-2μg/ml for 30 minutes at RT
Protein Array Assay dependent

Note :

IHC-P
Staining of formalin-fixed tissues is enhanced by heating tissue sections in 10mM Tris buffer with 1mM EDTA, pH 9.0, for 45 min at 95ºC followed by cooling at RT for 20 minutes.
Not tested in other applications.

Calculated MW

125 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

10mM PBS, 0.05% BSA

Preservative

0.05% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.2 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant human CD163 fragment (around aa 43-196) (Exact sequence is proprietary)

Purification

Protein A/G purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

CD163 , CD163 molecule , M130 , MM130 , SCARI1

Cellular Localization

Secreted,Cell membrane

Background

The protein encoded by this gene is a member of the scavenger receptor cysteine-rich (SRCR) superfamily, and is exclusively expressed in monocytes and macrophages. It functions as an acute phase-regulated receptor involved in the clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages, and may thereby protect tissues from free hemoglobin-mediated oxidative damage. This protein may also function as an innate immune sensor for bacteria and inducer of local inflammation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011]

Database

Research Area

DATA IMAGES

Anti-CD163 antibody [M130/1210] used in IHC (Paraffin sections) (IHC-P). GTX18027

GTX18027 IHC-P Image

IHC-P analysis of human lymph node tissue using GTX18027 CD163 antibody [M130/1210].

Anti-CD163 antibody [M130/1210] used in IHC (Paraffin sections) (IHC-P). GTX18027

GTX18027 IHC-P Image

IHC-P analysis of human histiocytoma tissue using GTX18027 CD163 antibody [M130/1210].

Anti-CD163 antibody [M130/1210] used in Western Blot (WB). GTX18027

GTX18027 WB Image

WB analysis of spleen tissue lysate using GTX18027 CD163 antibody [M130/1210].

Anti-CD163 antibody [M130/1210] used in Protein Array (Protein Array). GTX18027

GTX18027 Protein Array Image

Analysis of Protein Array containing more than 19,000 full-length human proteins using CD163 Mouse Monoclonal Antibody (M130/1210). Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD’s) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD’s) between the Z-score. S-score therefore represents the relative target specificity of a Monoclonal Antibody to its intended target. A Monoclonal Antibody is considered to specific to its intended target if the Monoclonal Antibody has an S-score of at least 2.5. For example, if a Monoclonal Antibody binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that Monoclonal Antibody to protein X is equal to 29.

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 529