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CD163 antibody [M130/3708R]

Anti-CD163 antibody [M130/3708R] used in IHC (Paraffin sections) (IHC-P). GTX02599
Anti-CD163 antibody [M130/3708R] used in IHC (Paraffin sections) (IHC-P). GTX02599

Cat. No. GTX02599

Host

 Rabbit

Clonality

 Monoclonal

Clone Name

 M130/3708R

Isotype

 IgG

Application

 IHC-P, ELISA

Reactivity

 Human
Package
100 μg ($529)
See all CD163 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-P 1-2 μg/ml
ELISA Assay dependent

Note :

IHC-P
Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris buffer with 1mM EDTA (pH 9.0) for 45 min at 95ºC followed by cooling at RT for 20 minutes.

ELISA
For ELISA coating, recommend using BSA-free format (please contact us for PBS only format).
Not tested in other applications.

Calculated MW

125 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 0.05% BSA

Preservative

0.05% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.

Concentration

200 μg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Synthetic peptide corresponding to human CD163 residues within aa1056-1156

Purification

Protein A/G purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

CD163 molecule , M130 , MM130 , SCARI1

Background

The protein encoded by this gene is a member of the scavenger receptor cysteine-rich (SRCR) superfamily, and is exclusively expressed in monocytes and macrophages. It functions as an acute phase-regulated receptor involved in the clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages, and may thereby protect tissues from free hemoglobin-mediated oxidative damage. This protein may also function as an innate immune sensor for bacteria and inducer of local inflammation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011]

Database

Research Area

DATA IMAGES

Anti-CD163 antibody [M130/3708R] used in IHC (Paraffin sections) (IHC-P). GTX02599

GTX02599 IHC-P Image

IHC-P analysis of human tonsil tissue section using GTX02599 CD163 antibody [M130/3708R].

Anti-CD163 antibody [M130/3708R] used in IHC (Paraffin sections) (IHC-P). GTX02599

GTX02599 IHC-P Image

IHC-P analysis of human histiocytoma tissue section using GTX02599 CD163 antibody [M130/3708R].

REFERENCE

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REVIEW

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Package List Price ($)
$ 529