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CD163 antibody

Anti-CD163 antibody used in IHC (Paraffin sections) (IHC-P). GTX35247
Anti-CD163 antibody used in IHC (Paraffin sections) (IHC-P). GTX35247
Anti-CD163 antibody used in IHC (Paraffin sections) (IHC-P). GTX35247
Anti-CD163 antibody used in IHC (Paraffin sections) (IHC-P). GTX35247
Anti-CD163 antibody used in Western Blot (WB). GTX35247
Anti-CD163 antibody used in IHC (Paraffin sections) (IHC-P). GTX35247

Cat. No. GTX35247

Reference 3

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P, FACS

Reactivity

 Human, Mouse, Rat, Pig
Package
100 μg ($399)
See all CD163 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:300-1000
IHC-P 1:50-400
FACS Assay dependent
Not tested in other applications.

Calculated MW

125 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

1% BSA, 50% Glycerol

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

KLH conjugated synthetic peptide derived from human CD163(800-850).

Purification

Protein A purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

CD163 molecule , M130 , MM130 , SCARI1

Background

The protein encoded by this gene is a member of the scavenger receptor cysteine-rich (SRCR) superfamily, and is exclusively expressed in monocytes and macrophages. It functions as an acute phase-regulated receptor involved in the clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages, and may thereby protect tissues from free hemoglobin-mediated oxidative damage. This protein may also function as an innate immune sensor for bacteria and inducer of local inflammation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011]

Database

Research Area

DATA IMAGES

Anti-CD163 antibody used in IHC (Paraffin sections) (IHC-P). GTX35247

GTX35247 IHC-P Image

IHC-P analysis of human testis tissue using GTX35247 CD163 antibody.
Dilution : 1:100

Anti-CD163 antibody used in IHC (Paraffin sections) (IHC-P). GTX35247

GTX35247 IHC-P Image

IHC-P analysis of human testis tissue using GTX35247 CD163 antibody.
Dilution : 1:100

Anti-CD163 antibody used in IHC (Paraffin sections) (IHC-P). GTX35247

GTX35247 IHC-P Image

IHC-P analysis of mouse intestine tissue using GTX35247 CD163 antibody.
Dilution : 1:200

Anti-CD163 antibody used in IHC (Paraffin sections) (IHC-P). GTX35247

GTX35247 IHC-P Image

IHC-P analysis of rat colon tissue using GTX35247 CD163 antibody.

Anti-CD163 antibody used in Western Blot (WB). GTX35247

GTX35247 WB Image

WB analysis of various samples using GTX35247 CD163 antibody.
Dilution : 1:200
Lane 1 : rat brain lysates
Lane 2 : mouse uterus lysates

Anti-CD163 antibody used in IHC (Paraffin sections) (IHC-P). GTX35247

GTX35247 IHC-P Image

IHC-P analysis of rat colon tissue using GTX35247 CD163 antibody.

REFERENCE

Application Reference

SK Mohamed et al. J Neuroimmune Pharmacol 2023; Sertraline Pre-Treatment Attenuates Hemorrhagic Transformation Induced in Rats after Cerebral Ischemia Reperfusion via Down Regulation of Neuronal CD163: Involvement of M1/M2 Polarization Interchange and Inhibiting Autophagy
Application : IHC-P
Aushia Tanzih Al Haq et al. Cell Death Dis 2022; 13 (1) : 49 Targeting prooxidant MnSOD effect inhibits triple-negative breast cancer (TNBC) progression and M2 macrophage functions under the oncogenic stress.
Application : IHC-P
Reactivity : Human
Wang T et al. J Inflamm Res 2021; 14 : 1085-1110 Restraint Stress in Hypertensive Rats Activates the Intestinal Macrophages and Reduces Intestinal Barrier Accompanied by Intestinal Flora Dysbiosis.
Application : IHC-P
Reactivity : Rat
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SDS
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399