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CD163 antibody

Anti-CD163 antibody used in Western Blot (WB). GTX35248
Anti-CD163 antibody used in IHC (Frozen sections) (IHC-Fr). GTX35248
Anti-CD163 antibody used in Western Blot (WB). GTX35248
Anti-CD163 antibody used in IHC (Paraffin sections) (IHC-P). GTX35248

Cat. No. GTX35248

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P, IHC-Fr

Reactivity

 Human, Mouse, Rat, Guinea pig
Package
100 μg ($459)
See all CD163 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB Assay dependent
IHC-P 1: 100-600
IHC-Fr Assay dependent
Not tested in other applications.

Calculated MW

125 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

10mM PBS

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.5 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

KLH conjugated synthetic peptide derived from human CD163.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

CD163 molecule , M130 , MM130 , SCARI1

Background

The protein encoded by this gene is a member of the scavenger receptor cysteine-rich (SRCR) superfamily, and is exclusively expressed in monocytes and macrophages. It functions as an acute phase-regulated receptor involved in the clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages, and may thereby protect tissues from free hemoglobin-mediated oxidative damage. This protein may also function as an innate immune sensor for bacteria and inducer of local inflammation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011]

Database

Research Area

DATA IMAGES

Anti-CD163 antibody used in Western Blot (WB). GTX35248

GTX35248 WB Image

WB analysis of guniea pig lymph (Lane 1), rat brain (Lane 2), mouse stomach (Lane 3), rat rectum (Lane 4), human gallbladder (Lane 5), human lung cancer (Lane 6) tissue lysates using GTX35248 CD163 antibody.
Dilution : 0.5μg/ml

Anti-CD163 antibody used in IHC (Frozen sections) (IHC-Fr). GTX35248

GTX35248 IHC-Fr Image

IHC-Fr analysis of mouse skin tissue using GTX35248 CD163 antibody.
Dilution : 1:100

Anti-CD163 antibody used in Western Blot (WB). GTX35248

GTX35248 WB Image

WB analysis of rat lung tissue lysate using GTX35248 CD163 antibody.
Dilution : 1:500

Anti-CD163 antibody used in IHC (Paraffin sections) (IHC-P). GTX35248

GTX35248 IHC-P Image

IHC-P analysis of mouse stomach tissue using GTX35248 CD163 antibody.
Dilution : 2.5μg/ml

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 459