GeneTex
United States (US)

CD163 antibody

GTX35248_20190129_WB_19012901_913.jpg
GTX35248_20190129_IHC-Fr_19012901_830.jpg
GTX35248_20190129_WB_1_19012901_741.jpg
GTX35248_20190129_IHC-P_19012901_733.jpg

Cat No. GTX35248

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, IHC-P, IHC-Fr
Reactivity Human, Mouse, Rat, Guinea pig
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB Assay dependent
IHC-P 1: 100-600
IHC-Fr Assay dependent
Not tested in other applications.

Calculated MW

125 kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

10 mM PBS, 0.02% sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20º C or below. Avoid multiple freeze-thaw cycles.

Concentration

0.5 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

KLH conjugated synthetic peptide derived from human CD163. Please contact us for the exact immunogen sequence.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Cd163 Molecule,M130,Mm130,Scari1,Cd163

Cellular Localization

Cell membrane,Secreted

Background

The protein encoded by this gene is a member of the scavenger receptor cysteine-rich (SRCR) superfamily, and is exclusively expressed in monocytes and macrophages. It functions as an acute phase-regulated receptor involved in the clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages, and may thereby protect tissues from free hemoglobin-mediated oxidative damage. This protein may also function as an innate immune sensor for bacteria and inducer of local inflammation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011]
DATA IMAGES
GTX35248_20190129_WB_19012901_913.jpg

GTX35248 WB Image

WB analysis of guniea pig lymph (Lane 1), rat brain (Lane 2), mouse stomach (Lane 3), rat rectum (Lane 4), human gallbladder (Lane 5), human lung cancer (Lane 6) tissue lysates using GTX35248 CD163 antibody.
Dilution : 0.5μg/ml

GTX35248_20190129_IHC-Fr_19012901_830.jpg

GTX35248 IHC-Fr Image

IHC-Fr analysis of mouse skin tissue using GTX35248 CD163 antibody.
Dilution : 1:100

GTX35248_20190129_WB_1_19012901_741.jpg

GTX35248 WB Image

WB analysis of rat lung tissue lysate using GTX35248 CD163 antibody.
Dilution : 1:500

GTX35248_20190129_IHC-P_19012901_733.jpg

GTX35248 IHC-P Image

IHC-P analysis of mouse stomach tissue using GTX35248 CD163 antibody.
Dilution : 2.5μg/ml

Package List Price ($)
$ 389