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CD177 antibody [MEM-166] (APC)

Anti-CD177 antibody [MEM-166] (APC) used in Flow cytometry (FACS). GTX79995

Cat. No. GTX79995

Reference 1

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 MEM-166

Isotype

 IgG1

Application

 FACS

Reactivity

 Human, Primate
Package
100 test ($329)
See all CD177 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
FACS 10 μl reagent / 100 μl of whole blood or 10⁶ cells in a suspension
Not tested in other applications.

Calculated MW

46 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

15mM Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE. Protect from light.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Human granulocytes

Purification

Purified by size-exclusion chromatography

Conjugation

Allophycocyanin (APC)

RRID

AB_11169427

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

CD177 , CD177 molecule , HNA2A , HNA2a , NB1 , NB1 GP , PRV1

Cellular Localization

Cell membrane,Membrane raft,Secreted,Cytoplasmic granule membrane,Cell projection,Lamellipodium

Background

This gene encodes a glycosyl-phosphatidylinositol (GPI)-linked cell surface glycoprotein that plays a role in neutrophil activation. The protein can bind platelet endothelial cell adhesion molecule-1 and function in neutrophil transmigration. Mutations in this gene are associated with myeloproliferative diseases. Over-expression of this gene has been found in patients with polycythemia rubra vera. Autoantibodies against the protein may result in pulmonary transfusion reactions, and it may be involved in Wegener's granulomatosis. A related pseudogene, which is adjacent to this gene on chromosome 19, has been identified. [provided by RefSeq, Apr 2014]

Database

Research Area

DATA IMAGES

Anti-CD177 antibody [MEM-166] (APC) used in Flow cytometry (FACS). GTX79995

GTX79995 FACS Image

FACS analysis of human peripheral blood using GTX79995 CD177 antibody [MEM-166] (APC).

REFERENCE

Clone Reference

Jankowska AM et al. Haematologica 2011; 96 (7):954-62 Loss of expression of neutrophil proteinase-3: a factor contributing to thrombotic risk in paroxysmal nocturnal hemoglobinuria.
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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 329