GeneTex

  • Country / Location Selection

United States (US)

CD18 antibody [C71/16]

Cat. No. GTX19580

Host

 Rat

Clonality

 Monoclonal

Clone Name

 C71/16

Isotype

 IgG2a

Application

 IHC-Fr, FACS, IP, IHC (Formalin)

Reactivity

 Mouse
Package
250 μg ($399)
See all CD18 products

APPLICATION

Application Note

FACS: Use 1μg for 10^6 cells. IHC-acetone fixed frozen tissue sections: Use at an assay dependent dilution. IP: Use at an assay dependent dilution. The antibody precipitates a (Mr 150/90 kDa) heterodimer from mouse leukocytes. Optimal dilutions/concentrations should be determined by the end user.

Calculated MW

85 kDa. ( Note )

Positive Control

The mouse CD18 antigen is present on mouse T-cells, B-cells, NK cells, monocytes, macrophages and granulocytes.

PROPERTIES

Form

Liquid

Buffer

0.01M PBS pH7.2, 1% BSA

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.5 mg/ml (Please refer to the vial label for the specific concentration.)

Immunogen

Cell membrane glycoproteins derived from BW5147 cells.

Purification

Protein G purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

integrin subunit beta 2 , CD18 , LAD , LCAMB , LFA-1 , MAC-1 , MF17 , MFI7

Cellular Localization

Cell membrane

Background

This gene encodes an integrin beta chain, which combines with multiple different alpha chains to form different integrin heterodimers. Integrins are integral cell-surface proteins that participate in cell adhesion as well as cell-surface mediated signalling. The encoded protein plays an important role in immune response and defects in this gene cause leukocyte adhesion deficiency. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014]

Database

Research Area

REFERENCE

There are currently no references for CD18 antibody [C71/16] (GTX19580). Be the first to share your publications with this product.
Submit a Reference

REVIEW

There are currently no reviews for CD18 antibody [C71/16] (GTX19580). Be the first to share your experience with this product.
Submit a Review
SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399