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CD18 antibody [YFC118.3] (Azide free)

Cat. No. GTX76241

Reference 1

Host

 Rat

Clonality

 Monoclonal

Clone Name

 YFC118.3

Isotype

 IgG2b

Application

 IHC-Fr, FACS, IP

Reactivity

 Human, Dog
Package
500 μg ($409)
See all CD18 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-Fr 1/1,000-1/5,000
FACS 1/50-1/100
IP Assay dependent

Note :

FACS
Use 10μl of the suggested working dilution to label 106 cells in 100μl.
Not tested in other applications.

Calculated MW

85 kDa. ( Note )

Positive Control

Tonsil

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

No preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Human neutrophil preparation

Purification

Protein G purified

Conjugation

Unconjugated

RRID

AB_377239

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

integrin subunit beta 2 , CD18 , LAD , LCAMB , LFA-1 , MAC-1 , MF17 , MFI7

Cellular Localization

Cell membrane

Background

This gene encodes an integrin beta chain, which combines with multiple different alpha chains to form different integrin heterodimers. Integrins are integral cell-surface proteins that participate in cell adhesion as well as cell-surface mediated signalling. The encoded protein plays an important role in immune response and defects in this gene cause leukocyte adhesion deficiency. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014]

Database

Research Area

REFERENCE

Clone Reference

Sindrilaru A et al. J Clin Invest 2011; 121 (3):985-97 An unrestrained proinflammatory * macrophage population induced by iron impairs wound healing in humans and mice.
Application : IHC-Fr
Reactivity : Human
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REVIEW

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SDS
PBS.pdf
Package List Price ($)
$ 409