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CD18 antibody [YFC118.3] (PE)

Anti-CD18 antibody [YFC118.3] (PE) used in Flow cytometry (FACS). GTX76239

Cat. No. GTX76239

Reference 1

Host

 Rat

Clonality

 Monoclonal

Clone Name

 YFC118.3

Isotype

 IgG2b

Application

 IHC-Fr, FACS

Reactivity

 Human, Dog, Guinea pig
Package
100 test ($489)
See all CD18 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-Fr Assay dependent
FACS Neat

Note :

FACS
Use 10μl of the suggested working dilution to label 106 cells or 100μl whole blood.
Not tested in other applications.

Calculated MW

85 kDa. ( Note )

Product Note

Clone YFC118.3 is a strong reactivity with Leucocytes (platelets negative).

PROPERTIES

Form

Liquid

Buffer

PBS, 1% BSA, 5% Sucrose

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE. Protect from light.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Human neutrophils.

Purification

Protein G purified

Conjugation

Phycoerythrin (PE)

RRID

AB_377237

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

integrin subunit beta 2 , CD18 , LAD , LCAMB , LFA-1 , MAC-1 , MF17 , MFI7

Cellular Localization

Cell membrane

Background

This gene encodes an integrin beta chain, which combines with multiple different alpha chains to form different integrin heterodimers. Integrins are integral cell-surface proteins that participate in cell adhesion as well as cell-surface mediated signalling. The encoded protein plays an important role in immune response and defects in this gene cause leukocyte adhesion deficiency. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014]

Database

Research Area

DATA IMAGES

Anti-CD18 antibody [YFC118.3] (PE) used in Flow cytometry (FACS). GTX76239

GTX76239 FACS Image

FACS analysis of human peripheral blood granulocytes using GTX76239 CD18 antibody [YFC118.3] (PE).

REFERENCE

Clone Reference

Sindrilaru A et al. J Clin Invest 2011; 121 (3):985-97 An unrestrained proinflammatory * macrophage population induced by iron impairs wound healing in humans and mice.
Application : IHC-Fr
Reactivity : Human
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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 489