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CD1a antibody [MTB1]

Anti-CD1a antibody [MTB1] used in IHC (Paraffin sections) (IHC-P). GTX01899

Cat. No. GTX01899

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 MTB1

Isotype

 IgG1

Application

 IHC-P

Reactivity

 Human
Package
500 μl ($639)
See all CD1a products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-P 1:50

Note :

IHC-P
The recommended fixative is 10% neutral-buffered formalin for paraffin-embedded tissue sections. Heat Induced Epitope Retreival (HIER) was performed in Epitope Retreival Solution pH6.
Not tested in other applications.

Calculated MW

37 kDa. ( Note )

Product Note

Some evidence of cross-reactivity with CD1b shown by reactivity with small focal groups of lymphocytes outside the germinal centers of tonsil.

PROPERTIES

Form

Liquid

Buffer

Tissue culture supernatant

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.

Antigen Species

Human

Immunogen

Prokaryotic recombinant fusion protein corresponding to the full external domain of the human CD1a molecule.

Purification

Unpurified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

CD1a molecule , CD1 , FCB6 , HTA1 , R4 , T6

Cellular Localization

Cell membrane , Endosome membrane

Background

This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to the plasma membrane and to recycling vesicles of the early endocytic system. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]

Database

Research Area

DATA IMAGES

Anti-CD1a antibody [MTB1] used in IHC (Paraffin sections) (IHC-P). GTX01899

GTX01899 IHC-P Image

IHC-P analysis of human thymoma tissue using GTX01899 CD1a antibody [MTB1]. Note the neoplastic cells show a moderate to strong and distinct membrane staining reaction.

REFERENCE

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REVIEW

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Package List Price ($)
$ 639