GeneTex

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United States (US)

CD1c antibody

Cat. No. GTX18216

Host

 Mouse

Clonality

 Monoclonal

Isotype

 IgG1

Application

 IP, RID

Reactivity

 Human
Package
100 μg ($399)
See all CD1c products

APPLICATION

Application Note

IP: Use at an assay dependent dilution. RID: Use at an assay dependent dilution. Optimal dilutions/concentrations should be determined by the end user.

Calculated MW

38 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

No preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

MOLT 4 cell line.

Purification

IgG fraction

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

CD1c molecule , BDCA1 , CD1 , CD1A , R7

Cellular Localization

Cell membrane , Endosome membrane , Lysosome

Background

This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene is broadly distributed throughout the endocytic system via a tyrosine-based motif in the cytoplasmic tail. Alternatively spliced transcript variants of this gene have been observed, but their full-length nature is not known. [provided by RefSeq, Jul 2008]

Database

Research Area

REFERENCE

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SDS
PBS.pdf
Package List Price ($)
$ 399
Custom Conjugations