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CD20 antibody [2H7] (APC-Cy7)

Cat. No. GTX00466-15

Reference 1

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 2H7

Isotype

 IgG2b

Application

 FACS

Reactivity

 Human, Primate
Package
100 test ($319)
See all CD20 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
FACS 4 μl reagent / 100 μl of whole blood or 10⁶ cells in a suspension
Not tested in other applications.

Calculated MW

33 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

15mM Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE. Protect from light.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Human tonsillar B cells

Purification

Purified by size-exclusion chromatography

Conjugation

Allophycocyanin-Cyanine7 (APC-Cy7) Wavelength

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption. Cy and CyDye are trademarks of GE Healthcare.

TARGET

Synonyms

B1 , Bp35 , CD20 , CVID5 , LEU16 , MS4A1 , MS4A2 , S7 , membrane spanning 4domains A1 , membrane spanning 4-domains A1

Cellular Localization

Cell membrane

Background

This gene encodes a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. This gene encodes a B-lymphocyte surface molecule which plays a role in the development and differentiation of B-cells into plasma cells. This family member is localized to 11q12, among a cluster of family members. Alternative splicing of this gene results in two transcript variants which encode the same protein. [provided by RefSeq, Jul 2008]

Database

Research Area

REFERENCE

Clone Reference

Kotani N et al. J Biol Chem 2012; 287 (44):37109-18 Fibroblast growth factor receptor 3 (FGFR3) associated with the CD20 antigen regulates the rituximab-induced proliferation inhibition in B-cell lymphoma cells.
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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 319