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CD20 antibody [L26]

Anti-CD20 antibody [L26] used in IHC (Paraffin sections) (IHC-P). GTX29475
Anti-CD20 antibody [L26] used in IHC (Paraffin sections) (IHC-P). GTX29475

Cat. No. GTX29475

Reference 5

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 L26

Isotype

 IgG2a

Application

 ICC/IF, IHC-P, IHC-Fr

Reactivity

 Human, Pig
Package
250 μl ($399)
See all CD20 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
ICC/IF Assay dependent
IHC-P Assay dependent
IHC-Fr Assay dependent
Not tested in other applications.

Calculated MW

33 kDa. ( Note )

Product Note

This antibody is specific to a 33 kDa polypeptide present on the majority of B cells in peripheral blood and lymphoid tissue and also with a minor component of 30 kDa. No reactivity with other haematopoietic cells has been observed.

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Human tonsil B cells

Purification

Purified IgG

Conjugation

Unconjugated

RRID

AB_368330

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

membrane spanning 4-domains A1 , B1 , Bp35 , CD20 , CVID5 , LEU-16 , MS4A2 , S7

Cellular Localization

Cell membrane

Background

This gene encodes a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. This gene encodes a B-lymphocyte surface molecule which plays a role in the development and differentiation of B-cells into plasma cells. This family member is localized to 11q12, among a cluster of family members. Alternative splicing of this gene results in two transcript variants which encode the same protein. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-CD20 antibody [L26] used in IHC (Paraffin sections) (IHC-P). GTX29475

GTX29475 IHC-P Image

Formalin fixed paraffin embedded human tonsil stained with CD20, B cell antibody (cat. # GTX71955).

Anti-CD20 antibody [L26] used in IHC (Paraffin sections) (IHC-P). GTX29475

GTX29475 IHC-P Image

GTX29475 - immunohistochemistry: Formalin fixed paraffin embedded human tonsil stained with CD20, B cell using ABC and Fast Red chromagen.

REFERENCE

Application Reference

Esaulova E et al. Cell Host Microbe 2021; 29 (2) : 165-178.e8 The immune landscape in tuberculosis reveals populations linked to disease and latency.
Reactivity : Human
Sun W et al. Nat Commun 2018; 9 (1) : 5127 B cells inhibit bone formation in rheumatoid arthritis by suppressing osteoblast differentiation.
Application : ICC/IF
Reactivity : Human

Clone Reference

M Clement et al. J Autoimmun 2015; 56:23-33 Upholding the T cell immune-regulatory function of CD31 inhibits the formation of T/B immunological synapses in vitro and attenuates the development of experimental autoimmune arthritis in vivo
Application : IHC-Fr
Reactivity : Human
Y Hisashi et al. Am J Transplant 2008; 8 (12):2516 - 26 Rejection of cardiac xenografts transplanted from alpha1,3-galactosyltransferase gene-knockout (GalT-KO) pigs to baboons
Application : IHC-P
Reactivity : Pig
G Moldenhauer et al. Blood 2006; 107 (6):2470-3 AID expression identifies interfollicular large B cells as putative precursors of mature B-cell malignancies
Application : IHC-Fr
Submit a Reference

REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399