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CD24 antibody [ALB9]

Cat. No. GTX19704

Reference 1

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 ALB9

Isotype

 IgG1

Application

 IHC-Fr, FACS, Functional Assay

Reactivity

 Human
Package
100 μg ($399)
See all CD24 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-Fr Assay dependent
FACS Assay dependent
Functional Assay Assay dependent
Not tested in other applications.

Calculated MW

8 kDa. ( Note )

Product Note

CD 24. The molecular weight of the recognized antigen is 35–45 kDa. Recognizes B cells from pre-B tomature-B stage. The ALB9 monoclonal antibody has been assigned to the CD24 cluster of differentiation atthe sixth International Workshop on Human Leucocyte Differentiation Antigens held in Kobe, Japan in 1996.

PROPERTIES

Form

Liquid

Buffer

PBS, 0.1% BSA

Preservative

No preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Human bone marrow malignant cells from a non-B, non-T acute leukemia.

Purification

Purified IgG

Conjugation

Unconjugated

RRID

AB_423696

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

CD24 molecule , CD24A

Background

This gene encodes a sialoglycoprotein that is expressed on mature granulocytes and B cells and modulates growth and differentiation signals to these cells. The precursor protein is cleaved to a short 32 amino acid mature peptide which is anchored via a glycosyl phosphatidylinositol (GPI) link to the cell surface. This gene was missing from previous genome assemblies, but is properly located on chromosome 6. Non-transcribed pseudogenes have been designated on chromosomes 1, 15, 20, and Y. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014]

Database

Research Area

REFERENCE

Application Reference

Guo W et al. Immun Inflamm Dis 2014; 2 (4) : 239-53 CD24 activates the NLRP3 inflammasome through c-Src kinase activity in a model of the lining epithelium of inflamed periodontal tissues.
Application : Functional Assay
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REVIEW

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SDS
PBS.pdf
Package List Price ($)
$ 399