GeneTex

  • Country / Location Selection

United States (US)

CD27 antibody [O323] (PE)

Anti-CD27 antibody [O323] (PE) used in Flow cytometry (FACS). GTX01457-08

Cat. No. GTX01457-08

Reference 416

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 O323

Isotype

 IgG1

Application

 FACS

Reactivity

 Human, Baboon, Cynomolgus monkey, Rhesus Monkey
Package
100 test ($209)
See all CD27 products
PRODUCT

Summary

The O323 antibody reacts with human CD27 (TNFRSF7), a cell surface homodimer of ≥ 55 kDa subunits, which provides co-stimulatory signaling in support of the T cell (TCR) and B cell (BCR) receptors. By comparison with CD28, whose TCR co-stimulatory signal can trigger cell proliferation, CD27 signaling appears to promote cell survival and differentiation to effector / memory stages. Also in contrast with CD28, the CD27 receptor may be shed following interaction with its ligand CD70, which is typically expressed on activated dendritic cells, T cells and B cells. With respect to B cells, CD27 is considered to be a phenotypic marker for memory B cells. CD27 has been included within a group of phenotypic markers for identifying human B regulatory cells (Bregs), a cell type proposed to regulate CD4+ T cell proliferation and Foxp3 / CTLA-4 expression in Treg cells. The O323 antibody may be used for analysis of CD27 expression on peripheral T cells, and is frequently used in combination with antibodies for IgD and IgM to distinguish naïve vs. memory B cell populations. For identification of Breg cells, this antibody has been used in combination with antibodies for CD25, CD1d, IL-10 and TGF-beta. The antibody is also reported for cross-reactivity with Baboon, Cynomolgus and Rhesus CD27.

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
FACS 0.25 μg (5 μl) for 10⁵-10⁸ cells in 100 μl sample per test
Not tested in other applications.

Calculated MW

29 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

10mM NaH₂PO₄, 150mM NaCl, 0.1% Gelatin

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE. Protect from light.

Concentration

0.05 mg/ml (Please refer to the vial label for the specific concentration.)

Purification

Purified by affinity chromatography
From tissue culture supernatant

Conjugation

Phycoerythrin (PE)

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

CD27 molecule , CD27 , S152 , S152. LPFS2 , T14 , TNFRSF7 , Tp55

Cellular Localization

Membrane

Background

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-CD27 antibody [O323] (PE) used in Flow cytometry (FACS). GTX01457-08

GTX01457-08 FACS Image

FACS analysis of human peripheral blood lymphocytes using GTX01457-08 CD27 antibody [O323] (PE).
Solid lone : primary antibody
Dashed line : isotype control
antibody amount : 0.25 μg (5 μl)

REFERENCE

Clone Reference

Bowyer G et al. J Exp Med 2020; 217 (7) Reduced Ebola vaccine responses in CMV+ young adults is associated with expansion of CD57+KLRG1+ T cells.
Badura R et al. Front Cell Infect Microbiol 2020; 10:347 Early ART in Acute HIV-1 Infection: Impact on the B-Cell Compartment.
Rivera-Correa J et al. PLoS Negl Trop Dis 2020; 14 (7):e0008466 Atypical memory B-cells and autoantibodies correlate with anemia during Plasmodium vivax complicated infections.
Kreye J et al. bioRxiv 2020; A SARS-CoV-2 neutralizing antibody protects from lung pathology in a COVID-19 hamster model.
Kriegsmann K et al. Cancers (Basel) 2020; 12 (8) Comparison of NGS and MFC Methods: Key Metrics in Multiple Myeloma MRD Assessment.
Show More +
Submit a Reference

REVIEW

There are currently no reviews for CD27 antibody [O323] (PE) (GTX01457-08). Be the first to share your experience with this product.
Submit a Review
Clone Reference
Tonnerre P et al. Nat Microbiol 2020; 5 (1):76-83 Evolution of the innate and adaptive immune response in women with acute Zika virus infection.
Callender LA et al. Aging Cell 2020; 19 (2):e13067 Mitochondrial mass governs the extent of human T cell senescence.
Starke CE et al. J Clin Invest 2020; 130 (2):789-798 SIV-specific CD8+ T cells are clonotypically distinct across lymphoid and mucosal tissues.
Suzuki T et al. J Clin Invest 2020; 130 (2):799-812 Severe fever with thrombocytopenia syndrome virus targets B cells in lethal human infections.
Lee E et al. J Virol 2020; 94 (3) Impact of Antiretroviral Therapy Duration on HIV-1 Infection of T Cells within Anatomic Sites.
Dubrovsky L et al. mBio 2020; 11 (1) Inhibition of HIV Replication by Apolipoprotein A-I Binding Protein Targeting the Lipid Rafts.
Terpstra ML et al. Immun Inflamm Dis 2020; 8 (1):80-92 Circulating mucosal-associated invariant T cells in subjects with recurrent urinary tract infections are functionally impaired.
Coppola M et al. Front Immunol 2020; 11:103 Cell-Mediated Immune Responses to in vivo-Expressed and Stage-Specific Mycobacterium tuberculosis Antigens in Latent and Active Tuberculosis Across Different Age Groups.
Harmon JR et al. NPJ Vaccines 2020; 5:17 Rift Valley fever virus vaccination induces long-lived, antigen-specific human T cell responses.
Rinc?n-Ar?valo H et al. Heliyon 2020; 6 (3):e03441 Low frequency of IL-10+ B cells in patients with atherosclerosis is related with inflammatory condition.
Smith MA et al. Sci Rep 2020; 10 (1):4462 Using the circulating proteome to assess type I interferon activity in systemic lupus erythematosus.
Einhaus J et al. Arthritis Res Ther 2020; 22 (1):66 Inhibition of effector B cells by ibrutinib in systemic sclerosis.
Cong Z et al. Front Microbiol 2020; 11:357 Does Mucosal B1 Activation Result in the Accumulation of Peak IgM During Chronic Intrarectal SIVmac239 Exposure to Protect Chinese-Origin Rhesus Macaques From Disease Progression?
Umeda M et al. Sci Rep 2020; 10 (1):6010 Thymus and Activation-regulated Chemokine as a Biomarker for IgG4-related Disease.
Vitall? J et al. Sci Rep 2020; 10 (1):6070 Polyfunctional HIV-1 specific response by CD8+ T lymphocytes expressing high levels of CD300a.
Anderson EJ et al. Vaccines (Basel) 2020; 8 (1) Plasmablast, Memory B Cell, CD4+ T Cell, and Circulating Follicular Helper T Cell Responses to a Non-Replicating Modified Vaccinia Ankara Vaccine.
Ainai A et al. Microbiol Immunol 2020; 64 (4):313-325 Human immune responses elicited by an intranasal inactivated H5 influenza vaccine.
Grifoni A et al. Cell 2020; 181 (7):1489-1501.e15 Targets of T Cell Responses to SARS-CoV-2 Coronavirus in Humans with COVID-19 Disease and Unexposed Individuals.
Santer DM et al. PLoS Pathog 2020; 16 (4):e1008515 Differential expression of interferon-lambda receptor 1 splice variants determines the magnitude of the antiviral response induced by interferon-lambda 3 in human immune cells.
Kong Y et al. Front Immunol 2020; 11:759 Brain Ischemia Significantly Alters microRNA Expression in Human Peripheral Blood Natural Killer Cells.
Gilmore W et al. J Neuroinflammation 2020; 17 (1):189 Repopulation of T, B, and NK cells following alemtuzumab treatment in relapsing-remitting multiple sclerosis.
G?lvez C et al. EBioMedicine 2020; 57:102830 Extremely low viral reservoir in treated chronically HIV-1-infected individuals.
Papagno L et al. Sci Rep 2020; 10 (1):11620 The TLR9 ligand CpG ODN 2006 is a poor adjuvant for the induction of de novo CD8+ T-cell responses in vitro.
Scharf L et al. J Virol 2020; 94 (14) Delayed Expression of PD-1 and TIGIT on HIV-Specific CD8 T Cells in Untreated HLA-B*57:01 Individuals Followed from Early Infection.
Arroyo Hornero R et al. Commun Biol 2020; 3 (1):375 CD70 expression determines the therapeutic efficacy of expanded human regulatory T cells.
Zhou T et al. SSRN 2020;:3639618 Structure-Based Design with Tag-Based Purification and In-Process Biotinylation Enable Streamlined Development of SARS-CoV-2 Spike Molecular Probes.
Guo N et al. Front Immunol 2020; 11:1466 A 34-Marker Panel for Imaging Mass Cytometric Analysis of Human Snap-Frozen Tissue.
Gruber CN et al. Immunity 2020; Complex Autoinflammatory Syndrome Unveils Fundamental Principles of JAK1 Kinase Transcriptional and Biochemical Function.
Colomb F et al. Cell Rep 2020; 32 (5):107991 Sialyl-LewisX Glycoantigen Is Enriched on Cells with Persistent HIV Transcription during Therapy.
Gantner P et al. Nat Commun 2020; 11 (1):4089 Single-cell TCR sequencing reveals phenotypically diverse clonally expanded cells harboring inducible HIV proviruses during ART.
Pierini S et al. JCI Insight 2020; 5 (16) Ovarian granulosa cell tumor characterization identifies FOXL2 as an immunotherapeutic target.
Forster AH et al. PLoS Med 2020; 17 (3):e1003024 Safety, tolerability, and immunogenicity of influenza vaccination with a high-density microarray patch: Results from a randomized, controlled phase I clinical trial.
H?usler D et al. Neurol Neuroimmunol Neuroinflamm 2020; 7 (3) Glatiramer acetate immune modulates B-cell antigen presentation in treatment of MS.
Fisher BS et al. PLoS One 2020; 15 (5):e0233577 Oral Immunization with HIV-1 Envelope SOSIP trimers elicits systemic immune responses and cross-reactive anti-V1V2 antibodies in non-human primates.
Rahman MA et al. Sci Rep 2020; 10 (1):10060 Mucosal-associated invariant T (MAIT) cells provide B-cell help in vaccinated and subsequently SIV-infected Rhesus Macaques.
Zhou T et al. bioRxiv 2020; Structure-Based Design with Tag-Based Purification and In-Process Biotinylation Enable Streamlined Development of SARS-CoV-2 Spike Molecular Probes.
Schulthei? C et al. Immunity 2020; 53 (2):442-455.e4 Next-Generation Sequencing of T and B Cell Receptor Repertoires from COVID-19 Patients Showed Signatures Associated with Severity of Disease.
Verstappen GM et al. J Autoimmun 2020; 109:102439 Gene expression profiling of epithelium-associated FcRL4+ B cells in primary Sj?gren's syndrome reveals a pathogenic signature.
Bowyer G et al. J Exp Med 2020; 217 (7) Reduced Ebola vaccine responses in CMV+ young adults is associated with expansion of CD57+KLRG1+ T cells.
Badura R et al. Front Cell Infect Microbiol 2020; 10:347 Early ART in Acute HIV-1 Infection: Impact on the B-Cell Compartment.
Rivera-Correa J et al. PLoS Negl Trop Dis 2020; 14 (7):e0008466 Atypical memory B-cells and autoantibodies correlate with anemia during Plasmodium vivax complicated infections.
Kreye J et al. bioRxiv 2020; A SARS-CoV-2 neutralizing antibody protects from lung pathology in a COVID-19 hamster model.
Kriegsmann K et al. Cancers (Basel) 2020; 12 (8) Comparison of NGS and MFC Methods: Key Metrics in Multiple Myeloma MRD Assessment.
Liu M et al. Cell Mol Immunol 2019; 16 (4):367-379 Type I interferons promote the survival and proinflammatory properties of transitional B cells in systemic lupus erythematosus patients.
Perugino CA et al. J Allergy Clin Immunol 2019; 143 (2):736-745.e6 Identification of galectin-3 as an autoantigen in patients with IgG4-related disease.
Rozmus J et al. Biol Blood Marrow Transplant 2019; 25 (3):451-458 Comprehensive B Cell Phenotyping Profile for Chronic Graft-versus-Host Disease Diagnosis.
Neu KE et al. J Clin Invest 2019; 129 (1):93-105 Spec-seq unveils transcriptional subpopulations of antibody-secreting cells following influenza vaccination.
Fu J et al. Cell Stem Cell 2019; 24 (2):227-239.e8 Human Intestinal Allografts Contain Functional Hematopoietic Stem and Progenitor Cells that Are Maintained by a Circulating Pool.
Lechner A et al. Oncoimmunology 2019; 8 (3):1535293 Tumor-associated B cells and humoral immune response in head and neck squamous cell carcinoma.
Montel-Hagen A et al. Cell Stem Cell 2019; 24 (3):376-389.e8 Organoid-Induced Differentiation of Conventional T Cells from Human Pluripotent Stem Cells.
Liu Y et al. Nat Commun 2019; 10 (1):324 Cross-lineage protection by human antibodies binding the influenza B hemagglutinin.
Tan HX et al. J Clin Invest 2019; 129 (2):850-862 Subdominance and poor intrinsic immunogenicity limit humoral immunity targeting influenza HA stem.
Bruner KM et al. Nature 2019; 566 (7742):120-125 A quantitative approach for measuring the reservoir of latent HIV-1 proviruses.
Franco LM et al. J Exp Med 2019; 216 (2):384-406 Immune regulation by glucocorticoids can be linked to cell type-dependent transcriptional responses.
Bouafia A et al. J Clin Invest 2019; 129 (3):1047-1060 Loss of ARHGEF1 causes a human primary antibody deficiency.
Helmold Hait S et al. J Virol 2019; 93 (4) Early T Follicular Helper Cell Responses and Germinal Center Reactions Are Associated with Viremia Control in Immunized Rhesus Macaques.
Laparra A et al. Front Immunol 2019; 10:117 The Frequencies of Immunosuppressive Cells in Adipose Tissue Differ in Human, Non-human Primate, and Mouse Models.
Good Z et al. Nat Biotechnol 2019; 37 (3):259-266 Proliferation tracing with single-cell mass cytometry optimizes generation of stem cell memory-like T cells.
Fromentin R et al. Nat Commun 2019; 10 (1):814 PD-1 blockade potentiates HIV latency reversal ex vivo in CD4+ T cells from ART-suppressed individuals.
Tardif V et al. Nat Commun 2019; 10 (1):823 Adenosine deaminase-1 delineates human follicular helper T cell function and is altered with HIV.
Garcia-Bates TM et al. J Virol 2019; 93 (5) Contrasting Roles of the PD-1 Signaling Pathway in Dendritic Cell-Mediated Induction and Regulation of HIV-1-Specific Effector T Cell Functions.
Pardons M et al. PLoS Pathog 2019; 15 (2):e1007619 Single-cell characterization and quantification of translation-competent viral reservoirs in treated and untreated HIV infection.
van der Burg M et al. Front Immunol 2019; 10:246 The EuroFlow PID Orientation Tube for Flow Cytometric Diagnostic Screening of Primary Immunodeficiencies of the Lymphoid System.
Nivarthi UK et al. EBioMedicine 2019; 41:465-478 Longitudinal analysis of acute and convalescent B cell responses in a human primary dengue serotype 2 infection model.
Fang L et al. J Exp Clin Cancer Res 2019; 38 (1):123 Targeting late-stage non-small cell lung cancer with a combination of DNT cellular therapy and PD-1 checkpoint blockade.
Borcoman E et al. Oncoimmunology 2019; 8 (5):e1581556 Inhibition of PI3K pathway increases immune infiltrate in muscle-invasive bladder cancer.
Remmerswaal EBM et al. Eur J Immunol 2019; 49 (5):694-708 Expression of IL-7Rα and KLRG1 defines functionally distinct CD8+ T-cell populations in humans.
Jim?nez-Saiz R et al. J Allergy Clin Immunol 2019; 144 (1):336-339.e6 Human BCR analysis of single-sorted, putative IgE+ memory B cells in food allergy.
Ye Y et al. Arthritis Res Ther 2019; 21 (1):92 Iguratimod represses B cell terminal differentiation linked with the inhibition of PKC/EGR1 axis.
Burlion A et al. Oncoimmunology 2019; 8 (7):1596005 A novel combination of chemotherapy and immunotherapy controls tumor growth in mice with a human immune system.
Pawley DC et al. ACS Omega 2019; 4 (4):6808-6818 Highly Sensitive and Selective Direct Detection of Zika Virus Particles in Human Bodily Fluids for Accurate Early Diagnosis of Infection.
Pastore A et al. Nat Commun 2019; 10 (1):1874 Corrupted coordination of epigenetic modifications leads to diverging chromatin states and transcriptional heterogeneity in CLL.
Yang R et al. Front Immunol 2019; 10:913 IL-12 Expands and Differentiates Human Vγ2Vδ2 T Effector Cells Producing Antimicrobial Cytokines and Inhibiting Intracellular Mycobacterial Growth.
Terahara K et al. BMC Res Notes 2019; 12 (1):242 A CCR5+ memory subset within HIV-1-infected primary resting CD4+ T cells is permissive for replication-competent, latently infected viruses in vitro.
Staniek J et al. Front Immunol 2019; 10:951 TRAIL-R1 and TRAIL-R2 Mediate TRAIL-Dependent Apoptosis in Activated Primary Human B Lymphocytes.
Gaiti F et al. Nature 2019; 569 (7757):576-580 Epigenetic evolution and lineage histories of chronic lymphocytic leukaemia.
Beaussant-Cohen S et al. J Allergy Clin Immunol 2019; 144 (2):606-608.e4 Combined immunodeficiency in a patient with c-Rel deficiency.
Gadalla R et al. Front Oncol 2019; 9:415 Validation of CyTOF Against Flow Cytometry for Immunological Studies and Monitoring of Human Cancer Clinical Trials.
Del Prete GQ et al. JCI Insight 2019; 4 (11) TLR7 agonist administration to SIV-infected macaques receiving early initiated cART does not induce plasma viremia.
van Dongen JJM et al. Front Immunol 2019; 10:1271 EuroFlow-Based Flowcytometric Diagnostic Screening and Classification of Primary Immunodeficiencies of the Lymphoid System.
Fehres CM et al. Front Immunol 2019; 10:1368 APRIL Induces a Novel Subset of IgA+ Regulatory B Cells That Suppress Inflammation via Expression of IL-10 and PD-L1.
Burel JG et al. Elife 2019; 8 Circulating T cell-monocyte complexes are markers of immune perturbations.
Pu?nik J et al. J Virol 2019; 93 (14) Expansion of Stem Cell-Like CD4+ Memory T Cells during Acute HIV-1 Infection Is Linked to Rapid Disease Progression.
Han Q et al. Nat Commun 2019; 10 (1):2898 Difficult-to-neutralize global HIV-1 isolates are neutralized by antibodies targeting open envelope conformations.
Lau EYM et al. Clin Exp Immunol 2019; 197 (2):205-213 Type 2 diabetes is associated with the accumulation of senescent T cells.
Kurupati RK et al. Aging (Albany NY) 2019; 11 (13):4367-4381 Age-related changes in B cell metabolism.
Iversen R et al. Proc Natl Acad Sci U S A 2019; 116 (30):15134-15139 Efficient T cell-B cell collaboration guides autoantibody epitope bias and onset of celiac disease.
Kato R et al. Front Immunol 2019; 10:1619 CD4+CD25+LAG3+ T Cells With a Feature of Th17 Cells Associated With Systemic Lupus Erythematosus Disease Activity.
Nelson AN et al. J Virol 2019; 93 (15) Simian-Human Immunodeficiency Virus SHIV.CH505-Infected Infant and Adult Rhesus Macaques Exhibit Similar Env-Specific Antibody Kinetics, despite Distinct T-Follicular Helper and Germinal Center B Cell Landscapes.
Wu H et al. Blood Adv 2019; 3 (14):2153-2163 Assessment of TCR signal strength of antigen-specific memory CD8+ T cells in human blood.
Cho A et al. Cell Rep 2019; 28 (4):909-922.e6 Single-Cell Analysis Suggests that Ongoing Affinity Maturation Drives the Emergence of Pemphigus Vulgaris Autoimmune Disease.
Oll? Hurtado M et al. PLoS One 2019; 14 (8):e0216373 Tumor infiltrating lymphocytes expanded from pediatric neuroblastoma display heterogeneity of phenotype and function.
Naluyima P et al. J Immunol 2019; 203 (8):2210-2221 Terminal Effector CD8 T Cells Defined by an IKZF2+IL-7R- Transcriptional Signature Express FcγRIIIA, Expand in HIV Infection, and Mediate Potent HIV-Specific Antibody-Dependent Cellular Cytotoxicity.
Fajgenbaum DC et al. J Clin Invest 2019; 129 (10):4451-4463 Identifying and targeting pathogenic PI3K/AKT/mTOR signaling in IL-6-blockade-refractory idiopathic multicentric Castleman disease.
Rodriguez R et al. J Exp Med 2019; 216 (12):2800-2818 Concomitant PIK3CD and TNFRSF9 deficiencies cause chronic active Epstein-Barr virus infection of T cells.
McLeod B et al. Nat Commun 2019; 10 (1):4328 Potent antibody lineage against malaria transmission elicited by human vaccination with Pfs25.
Beltr?n E et al. J Clin Invest 2019; 129 (11):4758-4768 Early adaptive immune activation detected in monozygotic twins with prodromal multiple sclerosis.
Gros A et al. J Clin Invest 2019; 129 (11):4992-5004 Recognition of human gastrointestinal cancer neoantigens by circulating PD-1+ lymphocytes.
Winklmeier S et al. Neurol Neuroimmunol Neuroinflamm 2019; 6 (6):625 Identification of circulating MOG-specific B cells in patients with MOG antibodies.
Henry C et al. J Virol 2019; 93 (21) Monoclonal Antibody Responses after Recombinant Hemagglutinin Vaccine versus Subunit Inactivated Influenza Virus Vaccine: a Comparative Study.
Bocharnikov AV et al. JCI Insight 2019; 4 (20) PD-1hiCXCR5- T peripheral helper cells promote B cell responses in lupus via MAF and IL-21.
Upasani V et al. Front Immunol 2019; 10:2500 Impaired Antibody-Independent Immune Response of B Cells in Patients With Acute Dengue Infection.
Onodera T et al. J Immunol 2019; 203 (12):3282-3292 Immune-Focusing Properties of Virus-like Particles Improve Protective IgA Responses.
Rivera-Correa J et al. Elife 2019; 8 Atypical memory B-cells are associated with Plasmodium falciparum anemia through anti-phosphatidylserine antibodies.
Auladell M et al. Clin Transl Immunology 2019; 8 (11):e01090 Distinguishing naive- from memory-derived human B cells during acute responses.
Pinto D et al. Cell Host Microbe 2019; 26 (5):623-637.e8 Structural Basis for Broad HIV-1 Neutralization by the MPER-Specific Human Broadly Neutralizing Antibody LN01.
Eckl-Dorna J et al. EBioMedicine 2019; 50:421-432 Two years of treatment with the recombinant grass pollen allergy vaccine BM32 induces a continuously increasing allergen-specific IgG4 response.
Vaisman-Mentesh A et al. Front Immunol 2019; 10:2921 Molecular Landscape of Anti-Drug Antibodies Reveals the Mechanism of the Immune Response Following Treatment With TNFα Antagonists.
Ng MSF et al. Sci Immunol 2019; 4 (41) Helios enhances the preferential differentiation of human fetal CD4+ na?ve T cells into regulatory T cells.
Cossarizza A et al. Eur J Immunol 2019; 49 (10):1457-1973 Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition).
Nguyen S et al. Sci Transl Med 2019; 11 (523) Elite control of HIV is associated with distinct functional and transcriptional signatures in lymphoid tissue CD8+ T cells.
Jordan S et al. Cell 2019; 178 (5):1102-1114.e17 Dietary Intake Regulates the Circulating Inflammatory Monocyte Pool.
Callender LA et al. Aging Cell 2018; 17 (1) Human CD8+ EMRA T cells display a senescence-associated secretory phenotype regulated by p38 MAPK.
Renand A et al. J Allergy Clin Immunol 2018; 141 (5):1750-1760.e1 Synchronous immune alterations mirror clinical response during allergen immunotherapy.
Kiniry BE et al. Mucosal Immunol 2018; 11 (3):909-920 Detection of HIV-1-specific gastrointestinal tissue resident CD8+ T-cells in chronic infection.
Majri SS et al. J Immunol 2018; 200 (1):110-118 STAT5B: A Differential Regulator of the Life and Death of CD4+ Effector Memory T Cells.
Capsomidis A et al. Mol Ther 2018; 26 (2):354-365 Chimeric Antigen Receptor-Engineered Human Gamma Delta T Cells: Enhanced Cytotoxicity with Retention of Cross Presentation.
Amodio D et al. J Immunol 2018; 200 (2):538-550 Quantitative Multiplexed Imaging Analysis Reveals a Strong Association between Immunogen-Specific B Cell Responses and Tonsillar Germinal Center Immune Dynamics in Children after Influenza Vaccination.
Wang B et al. Nat Biotechnol 2018; 36 (2):152-155 Functional interrogation and mining of natively paired human VH:VL antibody repertoires.
Winter S et al. EMBO Mol Med 2018; 10 (2):188-199 Loss of RASGRP1 in humans impairs T-cell expansion leading to Epstein-Barr virus susceptibility.
Hirsch AJ et al. Nat Commun 2018; 9 (1):263 Zika virus infection in pregnant rhesus macaques causes placental dysfunction and immunopathology.
Kiniry BE et al. J Immunol 2018; 200 (5):1876-1888 Differential Expression of CD8+ T Cell Cytotoxic Effector Molecules in Blood and Gastrointestinal Mucosa in HIV-1 Infection.
Noyan K et al. Front Immunol 2018; 9:19 Human Immunodeficiency Virus Type-1 Elite Controllers Maintain Low Co-Expression of Inhibitory Receptors on CD4+ T Cells.
Kagoya Y et al. Nat Med 2018; 24 (3):352-359 A novel chimeric antigen receptor containing a JAK-STAT signaling domain mediates superior antitumor effects.
Mamedov MR et al. Immunity 2018; 48 (2):350-363.e7 A Macrophage Colony-Stimulating-Factor-Producing γδ T Cell Subset Prevents Malarial Parasitemic Recurrence.
Wilson R et al. Brain 2018; 141 (4):1063-1074 Condition-dependent generation of aquaporin-4 antibodies from circulating B cells in neuromyelitis optica.
Blum LK et al. Eur J Immunol 2018; 48 (5):874-884 Circulating plasmablasts are elevated and produce pathogenic anti-endothelial cell autoantibodies in idiopathic pulmonary arterial hypertension.
Wang Z et al. Nat Commun 2018; 9 (1):824 Clonally diverse CD38+HLA-DR+CD8+ T cells persist during fatal H7N9 disease.
Niu J et al. Clin Exp Immunol 2018; 192 (2):206-212 Dissection of a circulating CD3+ CD20+ T cell subpopulation in patients with psoriasis.
Makuch M et al. Ann Neurol 2018; 83 (3):553-561 N-methyl-D-aspartate receptor antibody production from germinal center reactions: Therapeutic implications.
Jegaskanda S et al. J Virol 2018; 92 (9) Intranasal Live Influenza Vaccine Priming Elicits Localized B Cell Responses in Mediastinal Lymph Nodes.
Buggert M et al. PLoS Pathog 2018; 14 (4):e1006973 Limited immune surveillance in lymphoid tissue by cytolytic CD4+ T cells during health and HIV disease.
Martin LK et al. PLoS Pathog 2018; 14 (4):e1006991 Cross-sectional analysis of CD8 T cell immunity to human herpesvirus 6B.
Van Nieuwenhove E et al. J Allergy Clin Immunol 2018; 142 (2):699-702.e12 A kindred with mutant IKAROS and autoimmunity.
Lim SY et al. Sci Transl Med 2018; 10 (439) TLR7 agonists induce transient viremia and reduce the viral reservoir in SIV-infected rhesus macaques on antiretroviral therapy.
Huang H et al. Clin Immunol 2018; 193:1-9 23-valent pneumococcal polysaccharide vaccine elicits hierarchical antibody and cellular responses in healthy and tuberculosis-cured elderly, and HIV-1-infected subjects.
Rodrigues M et al. Nat Commun 2018; 9 (1):1866 Outlier response to anti-PD1 in uveal melanoma reveals germline MBD4 mutations in hypermutated tumors.
Bengsch B et al. Immunity 2018; 48 (5):1029-1045.e5 Epigenomic-Guided Mass Cytometry Profiling Reveals Disease-Specific Features of Exhausted CD8?T Cells.
Iwabuchi R et al. Front Immunol 2018; 9:1042 Introduction of Human Flt3-L and GM-CSF into Humanized Mice Enhances the Reconstitution and Maturation of Myeloid Dendritic Cells and the Development of Foxp3+CD4+ T Cells.
Fox A et al. Front Immunol 2018; 9:1141 Exposure of Human CD8+ T Cells to Type-2 Cytokines Impairs Division and Differentiation and Induces Limited Polarization.
Straetemans T et al. Front Immunol 2018; 9:1062 GMP-Grade Manufacturing of T Cells Engineered to Express a Defined γδTCR.
Wallin EF et al. Front Immunol 2018; 9:1184 The Calcineurin Inhibitor Tacrolimus Specifically Suppresses Human T Follicular Helper Cells.
Sayin I et al. J Exp Med 2018; 215 (6):1531-1542 Spatial distribution and function of T follicular regulatory cells in human lymph nodes.
Yassine HM et al. Sci Rep 2018; 8 (1):8628 Use of Hemagglutinin Stem Probes Demonstrate Prevalence of Broadly Reactive Group 1 Influenza Antibodies in Human Sera.
Setliff I et al. Cell Host Microbe 2018; 23 (6):845-854.e6 Multi-Donor Longitudinal Antibody Repertoire Sequencing Reveals the Existence of Public Antibody Clonotypes in HIV-1 Infection.
Moysi E et al. J Clin Invest 2018; 128 (7):3171-3185 Altered immune cell follicular dynamics in HIV infection following influenza vaccination.
Piper CJM et al. Front Immunol 2018; 9:1372 CD19+CD24hiCD38hi B Cells Are Expanded in Juvenile Dermatomyositis and Exhibit a Pro-Inflammatory Phenotype After Activation Through Toll-Like Receptor 7 and Interferon-α.
Renand A et al. Front Immunol 2018; 9:1408 Heterogeneity of Ara h Component-Specific CD4 T Cell Responses in Peanut-Allergic Subjects.
Miggelbrink AM et al. Blood 2018; 131 (26):2967-2977 B-cell differentiation and IL-21 response in IL2RG/JAK3 SCID patients after hematopoietic stem cell transplantation.
Duggal NA et al. Sci Rep 2018; 8 (1):10186 Innate and adaptive immune dysregulation in critically ill ICU patients.
Tasaki S et al. Nat Commun 2018; 9 (1):2755 Multi-omics monitoring of drug response in rheumatoid arthritis in pursuit of molecular remission.
Yeo L et al. J Clin Invest 2018; 128 (8):3460-3474 Autoreactive T effector memory differentiation mirrors β cell function in type 1 diabetes.
Kratchmarov R et al. Blood Adv 2018; 2 (14):1685-1690 TCF1 expression marks self-renewing human CD8+ T cells.
Blum LK et al. Front Immunol 2018; 9:1634 Robust B Cell Responses Predict Rapid Resolution of Lyme Disease.
Kim ST et al. J Immunol 2018; 201 (5):1359-1372 Human Extrafollicular CD4+ Th Cells Help Memory B Cells Produce Igs.
Vitall? J et al. Front Immunol 2018; 9:1709 Altered Expression of CD300a Inhibitory Receptor on CD4+ T Cells From Human Immunodeficiency Virus-1-Infected Patients: Association With Disease Progression Markers.
Egorov ES et al. Front Immunol 2018; 9:1618 The Changing Landscape of Naive T Cell Receptor Repertoire With Human Aging.
Sureshchandra S et al. Front Physiol 2018; 9:1089 Inflammatory Determinants of Pregravid Obesity in Placenta and Peripheral Blood.
Laban S et al. PLoS One 2018; 13 (8):e0200818 Heterogeneity of circulating CD8 T-cells specific to islet, neo-antigen and virus in patients with type 1 diabetes mellitus.
Xu H et al. J Immunol 2018; 201 (7):1994-2003 Impaired Development and Expansion of Germinal Center Follicular Th Cells in Simian Immunodeficiency Virus-Infected Neonatal Macaques.
Kardava L et al. Nat Immunol 2018; 19 (9):1001-1012 IgG3 regulates tissue-like memory B cells in HIV-infected individuals.
Bajor DL et al. Oncoimmunology 2018; 7 (10):e1468956 Long-term outcomes of a phase I study of agonist CD40 antibody and CTLA-4 blockade in patients with metastatic melanoma.
Dupont CD et al. mSphere 2018; 3 (4) Two Vaccines for Staphylococcus aureus Induce a B-Cell-Mediated Immune Response.
Agarwal D et al. Immun Ageing 2018; 15:19 Immune response to influenza vaccination in the elderly is altered by chronic medication use.
Blasi M et al. Commun Biol 2018; 1:134 IDLV-HIV-1 Env vaccination in non-human primates induces affinity maturation of antigen-specific memory B cells.
Hamilton JA et al. J Immunol 2018; 201 (8):2203-2208 Cutting Edge: Intracellular IFN-β and Distinct Type I IFN Expression Patterns in Circulating Systemic Lupus Erythematosus B Cells.
Yamamoto T et al. Data Brief 2018; 20:1965-1974 Data on B cell phenotypes in baboons with pig artery patch grafts receiving conventional immunosuppressive therapy.
Musich T et al. J Immunol 2018; 201 (8):2287-2302 Neutrophil Vaccination Dynamics and Their Capacity To Mediate B Cell Help in Rhesus Macaques.
Rosenberg BR et al. PLoS Pathog 2018; 14 (9):e1007290 Longitudinal transcriptomic characterization of the immune response to acute hepatitis C virus infection in patients with spontaneous viral clearance.
Thiemann M et al. Front Oncol 2018; 8:387 A Single-Chain-Based Hexavalent CD27 Agonist Enhances T Cell Activation and Induces Anti-Tumor Immunity.
Bradley T et al. Cell 2018; 175 (2):387-399.e17 RAB11FIP5 Expression and Altered Natural Killer Cell Function Are Associated with Induction of HIV Broadly Neutralizing Antibody Responses.
Davydov AN et al. Front Immunol 2018; 9:2309 Comparative Analysis of B-Cell Receptor Repertoires Induced by Live Yellow Fever Vaccine in Young and Middle-Age Donors.
Zissler UM et al. EBioMedicine 2018; 36:475-488 Early IL-10 producing B-cells and coinciding Th/Tr17 shifts during three year grass-pollen AIT.
Lagou V et al. Cell Rep 2018; 25 (3):798-810.e6 Genetic Architecture of Adaptive Immune System Identifies Key Immune Regulators.
Harms RZ et al. Front Immunol 2018; 9:2332 Abnormal T Cell Frequencies, Including Cytomegalovirus-Associated Expansions, Distinguish Seroconverted Subjects at Risk for Type 1 Diabetes.
Ferrian S et al. Front Immunol 2018; 9:2438 Frequency of Circulating CD4+Ki67+HLA-DR- T Regulatory Cells Prior to Treatment for Multidrug Resistant Tuberculosis Can Differentiate the Severity of Disease and Predict Time to Culture Conversion.
Milagres L et al. Front Immunol 2018; 9:2500 Baseline Circulating Activated TFH and Tissue-Like Exhausted B Cells Negatively Correlate With Meningococcal C Conjugate Vaccine Induced Antibodies in HIV-Infected Individuals.
Kuri-Maga?a H et al. Front Immunol 2018; 9:2679 Non-coding Class Switch Recombination-Related Transcription in Human Normal and Pathological Immune Responses.
Douam F et al. Nat Commun 2018; 9 (1):5031 Selective expansion of myeloid and NK cells in humanized mice yields human-like vaccine responses.
Bhaumik SK et al. Viruses 2018; 11 (1) Pre-Existing Dengue Immunity Drives a DENV-Biased Plasmablast Response in ZIKV-Infected Patient.
Passos LSA et al. Front Immunol 2018; 9:3015 Activation of Human CD11b+ B1 B-Cells by Trypanosoma cruzi-Derived Proteins Is Associated With Protective Immune Response in Human Chagas Disease.
Selb R et al. J Allergy Clin Immunol 2017; 139 (1):290-299.e4 CD23 surface density on B?cells is associated with IgE levels and determines IgE-facilitated allergen uptake, as well as activation of allergen-specific T?cells.
Wege AK et al. Oncotarget 2017; 8 (2):2731-2744 IL-15 enhances the anti-tumor activity of trastuzumab against breast cancer cells but causes fatal side effects in humanized tumor mice (HTM).
Kiniry BE et al. Mucosal Immunol 2017; 10 (4):1008-1020 Predominance of weakly cytotoxic, T-betLowEomesNeg CD8+ T-cells in human gastrointestinal mucosa: implications for HIV infection.
Radenkovic M et al. Clin Exp Immunol 2017; 187 (3):418-427 Characterization of resident lymphocytes in human pancreatic islets.
Izawa K et al. J Exp Med 2017; 214 (1):73-89 Inherited CD70 deficiency in humans reveals a critical role for the CD70-CD27 pathway in immunity to Epstein-Barr virus infection.
Tauriainen J et al. Sci Rep 2017; 7:40354 Perturbed CD8+ T cell TIGIT/CD226/PVR axis despite early initiation of antiretroviral treatment in HIV infected individuals.
Vander Heiden JA et al. J Immunol 2017; 198 (4):1460-1473 Dysregulation of B Cell Repertoire Formation in Myasthenia Gravis Patients Revealed through Deep Sequencing.
Schober T et al. Nat Commun 2017; 8:14209 A human immunodeficiency syndrome caused by mutations in CARMIL2.
Kagoya Y et al. JCI Insight 2017; 2 (2):e89580 Transient stimulation expands superior antitumor T cells for adoptive therapy.
Tuluc F et al. AIDS Res Hum Retroviruses 2017; 33 (2):133-142 Decreased PD-1 Expression on CD8 Lymphocyte Subsets and Increase in CD8?Tscm Cells in Children with HIV Receiving Raltegravir.
Crome SQ et al. Nat Med 2017; 23 (3):368-375 A distinct innate lymphoid cell population regulates tumor-associated T cells.
Yi JS et al. Front Neurol 2017; 8:34 B10 Cell Frequencies and Suppressive Capacity in Myasthenia Gravis Are Associated with Disease Severity.
Riou R et al. J Virol 2017; 91 (5) Severe Symptomatic Primary Human Cytomegalovirus Infection despite Effective Innate and Adaptive Immune Responses.
Zheng HY et al. Sci Rep 2017; 7 (1):37 Accelerated disease progression and robust innate host response in aged SIVmac239-infected Chinese rhesus macaques is associated with enhanced immunosenescence.
Singh AK et al. Front Immunol 2017; 8:260 High Interferon-γ Uniquely in Vδ1 T Cells Correlates with Markers of Inflammation and Axonal Damage in Early Multiple Sclerosis.
Hasan MS et al. Clin Exp Immunol 2017; 188 (2):311-322 Circulating NK cells and their subsets in Beh?et's disease.
Paris RM et al. Pathog Immun 2017; 2 (1):66-88 Lower Baseline Germinal Center Activity and Preserved Th1 Immunity Are Associated With Hepatitis B Vaccine Response in Treated HIV Infection.
Lu X et al. Nature 2017; 543 (7647):728-732 Effective combinatorial immunotherapy for castration-resistant prostate cancer.
Oja AE et al. Front Immunol 2017; 8:325 The Transcription Factor Hobit Identifies Human Cytotoxic CD4+ T Cells.
Seet CS et al. Nat Methods 2017; 14 (5):521-530 Generation of mature T cells from human hematopoietic stem and progenitor cells in artificial thymic organoids.
Kaczmarek DJ et al. PLoS One 2017; 12 (4):e0174465 Alterations of the NK cell pool in HIV/HCV co-infection.
Knox JJ et al. JCI Insight 2017; 2 (8) T-bet+ B cells are induced by human viral infections and dominate the HIV gp140 response.
Darboe A et al. Eur J Immunol 2017; 47 (6):1040-1050 Enhancement of cytokine-driven NK cell IFN-γ production after vaccination of HCMV infected Africans.
Domae E et al. Oncotarget 2017; 8 (28):45928-45942 Cytokine-mediated activation of human ex vivo-expanded Vγ9Vδ2 T cells.
Manion M et al. PLoS One 2017; 12 (5):e0175517 Vitamin D deficiency is associated with IL-6 levels and monocyte activation in HIV-infected persons.
Arumugakani G et al. J Immunol 2017; 198 (12):4618-4628 Early Emergence of CD19-Negative Human Antibody-Secreting Cells at the Plasmablast to Plasma Cell Transition.
Albuquerque AS et al. Front Immunol 2017; 8:543 Major CD4 T-Cell Depletion and Immune Senescence in a Patient with Chronic Granulomatous Disease.
Giltiay NV et al. Arthritis Res Ther 2017; 19 (1):91 Targeting CD22 with the monoclonal antibody epratuzumab modulates human B-cell maturation and cytokine production in response to Toll-like receptor 7 (TLR7) and B-cell receptor (BCR) signaling.
Qaqish A et al. J Immunol 2017; 198 (12):4753-4763 Adoptive Transfer of Phosphoantigen-Specific γδ T Cell Subset Attenuates Mycobacterium tuberculosis Infection in Nonhuman Primates.
Nguyen SM et al. PLoS Pathog 2017; 13 (5):e1006378 Highly efficient maternal-fetal Zika virus transmission in pregnant rhesus macaques.
Vujkovic-Cvijin I et al. Gut Microbes 2017; 8 (5):440-450 Limited engraftment of donor microbiome via one-time fecal microbial transplantation in treated HIV-infected individuals.
Shoda H et al. Arthritis Res Ther 2017; 19 (1):111 Increased serum concentrations of IL-1 beta, IL-21 and Th17 cells in overweight patients with rheumatoid arthritis.
Marcial GE et al. Front Immunol 2017; 8:655 Lactobacillus johnsonii N6.2 Modulates the Host Immune Responses: A Double-Blind, Randomized Trial in Healthy Adults.
Magnani DM et al. PLoS Negl Trop Dis 2017; 11 (6):e0005655 A human inferred germline antibody binds to an immunodominant epitope and neutralizes Zika virus.
Cho A et al. JCI Insight 2017; 2 (12) Robust memory responses against influenza vaccination in pemphigus patients previously treated with rituximab.
Pauthner M et al. Immunity 2017; 46 (6):1073-1088.e6 Elicitation of Robust Tier 2 Neutralizing Antibody Responses in Nonhuman Primates by HIV Envelope Trimer Immunization Using Optimized Approaches.
Rutishauser RL et al. AIDS Res Hum Retroviruses 2017; 33 (7):658-667 Early and Delayed Antiretroviral Therapy Results in Comparable Reductions in CD8+ T Cell Exhaustion Marker Expression.
Magri G et al. Immunity 2017; 47 (1):118-134.e8 Human Secretory IgM Emerges from Plasma Cells Clonally Related to Gut Memory B Cells and Targets Highly Diverse Commensals.
McCracken MK et al. PLoS Pathog 2017; 13 (8):e1006487 Impact of prior flavivirus immunity on Zika virus infection in rhesus macaques.
Metzler G et al. J Immunol 2017; 199 (7):2249-2260 The Autoimmune Risk Variant PTPN22 C1858T Alters B Cell Tolerance at Discrete Checkpoints and Differentially Shapes the Naive Repertoire.
Sanderson SL et al. Aging Cell 2017; 16 (6):1234-1243 In aged primary T cells, mitochondrial stress contributes to telomere attrition measured by a novel imaging flow cytometry assay.
Li Z et al. Front Immunol 2017; 8:991 Syphilis Infection Differentially Regulates the Phenotype and Function of γδ T Cells in HIV-1-Infected Patients Depends on the HIV-1 Disease Stage.
Bruno TC et al. Cancer Immunol Res 2017; 5 (10):898-907 Antigen-Presenting Intratumoral B Cells Affect CD4+ TIL Phenotypes in Non-Small Cell Lung Cancer Patients.
van den Broek T et al. Eur J Immunol 2017; 47 (11):1970-1981 Human neonatal thymectomy induces altered B-cell responses and autoreactivity.
Meeuwsen JAL et al. J Am Heart Assoc 2017; 6 (9) High Levels of (Un)Switched Memory B Cells Are Associated With Better Outcome in Patients With Advanced Atherosclerotic Disease.
Cl?net ML et al. Sci Rep 2017; 7 (1):11612 Peripheral human CD4+CD8+ T lymphocytes exhibit a memory phenotype and enhanced responses to IL-2, IL-7 and IL-15.
Wendel BS et al. Nat Commun 2017; 8 (1):531 Accurate immune repertoire sequencing reveals malaria infection driven antibody lineage diversification in young children.
Rakshit S et al. Sci Rep 2017; 7 (1):11948 Circulating Mycobacterium tuberculosis DosR latency antigen-specific, polyfunctional, regulatory IL10+ Th17 CD4 T-cells differentiate latent from active tuberculosis.
Keustermans G et al. PLoS One 2017; 12 (10):e0187068 Differential adipokine receptor expression on circulating leukocyte subsets in lean and obese children.
Magnani DM et al. J Virol 2017; 91 (22) Potent Plasmablast-Derived Antibodies Elicited by the National Institutes of Health Dengue Vaccine.
Ezeonyeji A et al. Front Immunol 2017; 8:1403 CD4 T-Cell Dysregulation in Psoriatic Arthritis Reveals a Regulatory Role for IL-22.
Eggers EL et al. JCI Insight 2017; 2 (22) Clonal relationships of CSF B cells in treatment-naive multiple sclerosis patients.
Santos RLA et al. Nat Commun 2017; 8 (1):1692 Structure of human immunoproteasome with a reversible and noncompetitive inhibitor that selectively inhibits activated lymphocytes.
Gomez-Tourino I et al. Nat Commun 2017; 8 (1):1792 T cell receptor β-chains display abnormal shortening and repertoire sharing in type 1 diabetes.
Nguyen TA et al. PLoS One 2017; 12 (11):e0188250 Maternal-Fetal rejection reactions are unconstrained in preeclamptic women.
Turaj AH et al. Cancer Cell 2017; 32 (6):777-791.e6 Antibody Tumor Targeting Is Enhanced by CD27 Agonists through Myeloid Recruitment.
Cosma G et al. Front Immunol 2017; 8:1771 Identifying the Presence of Prostate Cancer in Individuals with PSA Levels <20?ng ml-1 Using Computational Data Extraction Analysis of High Dimensional Peripheral Blood Flow Cytometric Phenotyping Data.
Gavegnano C et al. PLoS Pathog 2017; 13 (12):e1006740 Novel mechanisms to inhibit HIV reservoir seeding using Jak inhibitors.
Chamberlain N et al. J Clin Invest 2016; 126 (1):282-7 Rituximab does not reset defective early B cell tolerance checkpoints.
Lewis MJ et al. Arthritis Res Ther 2016; 18:5 Improved monitoring of clinical response in Systemic Lupus Erythematosus by longitudinal trend in soluble vascular cell adhesion molecule-1.
Zumwalde NA et al. Cancer Prev Res (Phila) 2016; 9 (4):305-16 Analysis of Immune Cells from Human Mammary Ductal Epithelial Organoids Reveals Vδ2+ T Cells That Efficiently Target Breast Carcinoma Cells in the Presence of Bisphosphonate.
Roan F et al. J Immunol 2016; 196 (5):2051-2062 CD4+ Group 1 Innate Lymphoid Cells (ILC) Form a Functionally Distinct ILC Subset That Is Increased in Systemic Sclerosis.
Sugai S et al. Int J Oncol 2016; 48 (5):1794-804 Hepatocellular carcinoma cell sensitivity to Vγ9Vδ2 T lymphocyte-mediated killing is increased by zoledronate.
Sullivan RT et al. Malar J 2016; 15:139 B cell sub-types following acute malaria and associations with clinical immunity.
Mattoo H et al. J Allergy Clin Immunol 2016; 138 (3):825-838 Clonal expansion of CD4(+) cytotoxic T lymphocytes in patients with IgG4-related disease.
Meffre E et al. JCI Insight 2016; 1 (3) Maturational characteristics of HIV-specific antibodies in viremic individuals.
Eller MA et al. J Virol 2016; 90 (8):4005-4016 Expansion of Inefficient HIV-Specific CD8 T Cells during Acute Infection.
Rueda CM et al. J Immunol 2016; 196 (9):3706-15 Lipopolysaccharide-Induced Chorioamnionitis Promotes IL-1-Dependent Inflammatory FOXP3+ CD4+ T Cells in the Fetal Rhesus Macaque.
Beura LK et al. Nature 2016; 532 (7600):512-6 Normalizing the environment recapitulates adult human immune traits in laboratory mice.
Forcade E et al. Blood 2016; 127 (20):2489-97 Circulating T follicular helper cells with increased function during chronic graft-versus-host disease.
Zwang NA et al. Am J Transplant 2016; 16 (9):2624-38 Selective Sparing of Human Tregs by Pharmacologic Inhibitors of the Phosphatidylinositol 3-Kinase and MEK Pathways.
Wheatley AK et al. Sci Rep 2016; 6:26478 HIV-dependent depletion of influenza-specific memory B cells impacts B cell responsiveness to seasonal influenza immunisation.
Lima J et al. BMC Pregnancy Childbirth 2016; 16 (1):139 Characterization of B cells in healthy pregnant women from late pregnancy to post-partum: a prospective observational study.
Tan CT et al. Oncotarget 2016; 7 (29):44906-44918 Vδ2+ and α/? T cells show divergent trajectories during human aging.
Menard LC et al. JCI Insight 2016; 1 (9):e87310 B cells from African American lupus patients exhibit an activated phenotype.
Dudley DM et al. Nat Commun 2016; 7:12204 A rhesus macaque model of Asian-lineage Zika virus infection.
Jash A et al. J Immunol 2016; 197 (4):1159-68 ZBTB32 Restricts the Duration of Memory B Cell Recall Responses.
Lin PL et al. PLoS Pathog 2016; 12 (7):e1005739 PET CT Identifies Reactivation Risk in Cynomolgus Macaques with Latent M. tuberculosis.
Nagafuchi Y et al. Sci Rep 2016; 6:29338 Immunophenotyping of rheumatoid arthritis reveals a linkage between HLA-DRB1 genotype, CXCR4 expression on memory CD4(+) T cells, and disease activity.
Akiyama M et al. Arthritis Res Ther 2016; 18:167 Enhanced IgG4 production by follicular helper 2?T cells and the involvement of follicular helper 1?T cells in the pathogenesis of IgG4-related disease.
Fromentin R et al. PLoS Pathog 2016; 12 (7):e1005761 CD4+ T Cells Expressing PD-1, TIGIT and LAG-3 Contribute to HIV Persistence during ART.
Woda M et al. J Infect Dis 2016; 214 (7):1001-9 Dynamics of Dengue Virus (DENV)-Specific B Cells in the Response to DENV Serotype 1 Infections, Using Flow Cytometry With Labeled Virions.
Schickel JN et al. Sci Immunol 2016; 1 (1) PTPN22 inhibition resets defective human central B cell tolerance.
Neumann L et al. J Immunol 2016; 197 (5):1801-8 Mucosal Inducible NO Synthase-Producing IgA+ Plasma Cells in Helicobacter pylori-Infected Patients.
Muir R et al. PLoS Pathog 2016; 12 (7):e1005777 Altered Memory Circulating T Follicular Helper-B Cell Interaction in Early Acute HIV Infection.
Calascibetta F et al. J Virol 2016; 90 (16):7541-7551 Antiretroviral Therapy in Simian Immunodeficiency Virus-Infected Sooty Mangabeys: Implications for AIDS Pathogenesis.
Kagoya Y et al. J Clin Invest 2016; 126 (9):3479-94 BET bromodomain inhibition enhances T cell persistence and function in adoptive immunotherapy models.
Blatt K et al. Oncotarget 2016; 7 (40):65627-65642 Evaluation of in vitro effects of various targeted drugs on plasma cells and putative neoplastic stem cells in patients with multiple myeloma.
Kurupati R et al. Oncotarget 2016; 7 (39):62898-62911 Race-related differences in antibody responses to the inactivated influenza vaccine are linked to distinct pre-vaccination gene expression profiles in blood.
Jiang J et al. Sci Rep 2016; 6:32320 Enhanced immune response of MAIT cells in tuberculous pleural effusions depends on cytokine signaling.
Zenarruzabeitia O et al. Sci Rep 2016; 6:32693 The expression and function of human CD300 receptors on blood circulating mononuclear cells are distinct in neonates and adults.
Pachnio A et al. PLoS Pathog 2016; 12 (9):e1005832 Cytomegalovirus Infection Leads to Development of High Frequencies of Cytotoxic Virus-Specific CD4+ T Cells Targeted to Vascular Endothelium.
Osuna CE et al. Nat Med 2016; 22 (12):1448-1455 Zika viral dynamics and shedding in rhesus and cynomolgus macaques.
Arroyo L et al. Clin Vaccine Immunol 2016; 23 (10):813-824 Multifunctional T Cell Response to DosR and Rpf Antigens Is Associated with Protection in Long-Term Mycobacterium tuberculosis-Infected Individuals in Colombia.
Mudd JC et al. J Infect Dis 2016; 214 (12):1808-1816 Inflammatory Function of CX3CR1+ CD8+ T Cells in Treated HIV Infection Is Modulated by Platelet Interactions.
Cui A et al. J Immunol 2016; 197 (9):3566-3574 A Model of Somatic Hypermutation Targeting in Mice Based on High-Throughput Ig Sequencing Data.
Wang Y et al. J Exp Med 2016; 213 (11):2413-2435 Dual T cell- and B cell-intrinsic deficiency in humans with biallelic RLTPR mutations.
Massaad MJ et al. J Clin Invest 2016; 126 (11):4219-4236 Deficiency of base excision repair enzyme NEIL3 drives increased predisposition to autoimmunity.
Yeung YA et al. Nat Commun 2016; 7:13376 Germline-encoded neutralization of a Staphylococcus aureus virulence factor by the human antibody repertoire.
Ryan PL et al. Proc Natl Acad Sci U S A 2016; 113 (50):14378-14383 Heterogeneous yet stable Vδ2(+) T-cell profiles define distinct cytotoxic effector potentials in healthy human individuals.
Tsunetsugu-Yokota Y et al. Front Microbiol 2016; 7:1944 Homeostatically Maintained Resting Naive CD4+ T Cells Resist Latent HIV Reactivation.
Aliota MT et al. PLoS Negl Trop Dis 2016; 10 (12):e0005168 Heterologous Protection against Asian Zika Virus Challenge in Rhesus Macaques.
Luo K et al. JCI Insight 2016; 1 (20):e88522 Tissue memory B cell repertoire analysis after ALVAC/AIDSVAX B/E gp120 immunization of rhesus macaques.
Tzeng SJ et al. J Vis Exp 2016; (118) The Isolation, Differentiation, and Quantification of Human Antibody-secreting B Cells from Blood: ELISpot as a Functional Readout of Humoral Immunity.
Nu?ez S et al. Sci Immunol 2016; 1 (6) The human thymus perivascular space is a functional niche for viral-specific plasma cells.
Jiang Z et al. Front Immunol 2016; 7:690 Anti-GPC3-CAR T Cells Suppress the Growth of Tumor Cells in Patient-Derived Xenografts of Hepatocellular Carcinoma.
Gros A et al. Nat Med 2016; 22 (4):433-8 Prospective identification of neoantigen-specific lymphocytes in the peripheral blood of melanoma patients.
Della-Torre E et al. Ann Rheum Dis 2015; 74 (12):2236-43 B-cell depletion attenuates serological biomarkers of fibrosis and myofibroblast activation in IgG4-related disease.
Li Z et al. Cell Mol Immunol 2015; 12 (5):604-14 Distortion of memory Vδ2 γδ T cells contributes to immune dysfunction in chronic HIV infection.
Woda M et al. J Immunol Methods 2015; 416:167-77 Fluorescently labeled dengue viruses as probes to identify antigen-specific memory B cells by multiparametric flow cytometry.
Van Eyck L Jr et al. J Allergy Clin Immunol 2015; 135 (1):283-7.e5 Hematopoietic stem cell transplantation rescues the immunologic phenotype and prevents vasculopathy in patients with adenosine deaminase 2 deficiency.
Zin?cker S et al. J Immunol 2015; 194 (3):929-39 The V gene repertoires of classical and atypical memory B cells in malaria-susceptible West African children.
Okada S et al. Immunol Cell Biol 2015; 93 (5):461-71 STAT3 signaling contributes to the high effector activities of interleukin-15-derived dendritic cells.
Andrews SF et al. J Virol 2015; 89 (6):3308-17 High preexisting serological antibody levels correlate with diversification of the influenza vaccine response.
Otomo T et al. J Cell Biol 2015; 208 (2):171-80 Mannose 6 phosphorylation of lysosomal enzymes controls B cell functions.
Harms RZ et al. PLoS One 2015; 10 (1):e0117335 Altered CD161 bright CD8+ mucosal associated invariant T (MAIT)-like cell dynamics and increased differentiation states among juvenile type 1 diabetics.
Freeman CM et al. J Transl Med 2015; 13:19 Design of a multi-center immunophenotyping analysis of peripheral blood, sputum and bronchoalveolar lavage fluid in the Subpopulations and Intermediate Outcome Measures in COPD Study (SPIROMICS).
Boyle MJ et al. J Infect Dis 2015; 212 (3):416-25 Effector Phenotype of Plasmodium falciparum-Specific CD4+ T Cells Is Influenced by Both Age and Transmission Intensity in Naturally Exposed Populations.
Lewis MJ et al. Am J Hum Genet 2015; 96 (2):221-34 UBE2L3 polymorphism amplifies NF-κB activation and promotes plasma cell development, linking linear ubiquitination to multiple autoimmune diseases.
McMaster SR et al. PLoS One 2015; 10 (2):e0115725 Memory T cells generated by prior exposure to influenza cross react with the novel H7N9 influenza virus and confer protective heterosubtypic immunity.
Shimizu S et al. Mol Ther Nucleic Acids 2015; 4:e227 RNAi-Mediated CCR5 Knockdown Provides HIV-1 Resistance to Memory T Cells in Humanized BLT Mice.
Simchoni N et al. J Immunol 2015; 194 (7):3035-44 TLR7- and TLR9-responsive human B cells share phenotypic and genetic characteristics.
Shen C et al. PLoS One 2015; 10 (3):e0116667 Reduced expression of CD27 by collagenase treatment: implications for interpreting b cell data in tissues.
Aybar LT et al. Clin Exp Immunol 2015; 180 (2):178-88 Reduced CD5(+) CD24(hi) CD38(hi) and interleukin-10(+) regulatory B cells in active anti-neutrophil cytoplasmic autoantibody-associated vasculitis permit increased circulating autoantibodies.
Pombo C et al. J Infect Dis 2015; 212 (9):1376-86 Elevated Expression of CD160 and 2B4 Defines a Cytolytic HIV-Specific CD8+ T-Cell Population in Elite Controllers.
Long AH et al. Nat Med 2015; 21 (6):581-90 4-1BB costimulation ameliorates T cell exhaustion induced by tonic signaling of chimeric antigen receptors.
Portugal S et al. Elife 2015; 4 Malaria-associated atypical memory B cells exhibit markedly reduced B cell receptor signaling and effector function.
Sullivan RT et al. PLoS Pathog 2015; 11 (5):e1004894 FCRL5 Delineates Functionally Impaired Memory B Cells Associated with Plasmodium falciparum Exposure.
Boisson B et al. J Exp Med 2015; 212 (6):939-51 Human HOIP and LUBAC deficiency underlies autoinflammation, immunodeficiency, amylopectinosis, and lymphangiectasia.
McCarthy NE et al. J Clin Invest 2015; 125 (8):3215-25 Azathioprine therapy selectively ablates human Vδ2? T cells in Crohn's disease.
Schnorfeil FM et al. J Hematol Oncol 2015; 8:93 T cells are functionally not impaired in AML: increased PD-1 expression is only seen at time of relapse and correlates with a shift towards the memory T cell compartment.
Amos JD et al. J Virol 2015; 89 (18):9485-98 Rapid Development of gp120-Focused Neutralizing B Cell Responses during Acute Simian Immunodeficiency Virus Infection of African Green Monkeys.
Roskin KM et al. Sci Transl Med 2015; 7 (302):302ra135 IgH sequences in common variable immune deficiency reveal altered B cell development and selection.
Pala F et al. J Clin Invest 2015; 125 (10):3941-51 Lentiviral-mediated gene therapy restores B cell tolerance in Wiskott-Aldrich syndrome patients.
Frederiksen J et al. PLoS One 2015; 10 (9):e0137635 Multidimensional Clusters of CD4+ T Cell Dysfunction Are Primarily Associated with the CD4/CD8 Ratio in Chronic HIV Infection.
Macauley MS et al. J Biol Chem 2015; 290 (50):30066-77 Unmasking of CD22 Co-receptor on Germinal Center B-cells Occurs by Alternative Mechanisms in Mouse and Man.
Klarenbeek PL et al. PLoS One 2015; 10 (10):e0140815 Somatic Variation of T-Cell Receptor Genes Strongly Associate with HLA Class Restriction.
Cubas R et al. J Immunol 2015; 195 (12):5625-36 Reversible Reprogramming of Circulating Memory T Follicular Helper Cell Function during Chronic HIV Infection.
Javed A et al. PLoS One 2015; 10 (11):e0142086 Noncytolytic CD8+ Cell Mediated Antiviral Response Represents a Strong Element in the Immune Response of Simian Immunodeficiency Virus-Infected Long-Term Non-Progressing Rhesus Macaques.
Paris RM et al. PLoS One 2015; 10 (12):e0144767 Selective Loss of Early Differentiated, Highly Functional PD1high CD4 T Cells with HIV Progression.
Cairo C et al. J Infect Dis 2014; 209 (10):1653-62 Cord blood Vγ2Vδ2 T cells provide a molecular marker for the influence of pregnancy-associated malaria on neonatal immunity.
Thomas MA et al. Vaccine 2014; 32 (7):872-80 Rhesus macaque rectal and duodenal tissues exhibit B-cell sub-populations distinct from peripheral blood that continuously secrete antigen-specific IgA in short-term explant cultures.
Cherukuri A et al. J Am Soc Nephrol 2014; 25 (7):1575-85 Immunologic human renal allograft injury associates with an altered IL-10/TNF-α expression ratio in regulatory B cells.
Verhoeven D et al. J Immunol 2014; 192 (7):3308-18 Enhanced innate antiviral gene expression, IFN-α, and cytolytic responses are predictive of mucosal immune recovery during simian immunodeficiency virus infection.
Pa?no T et al. PLoS One 2014; 9 (3):e92378 Phenotypic, genomic and functional characterization reveals no differences between CD138++ and CD138low subpopulations in multiple myeloma cell lines.
Gros A et al. J Clin Invest 2014; 124 (5):2246-59 PD-1 identifies the patient-specific CD8? tumor-reactive repertoire infiltrating human tumors.
Allen JL et al. Blood 2014; 123 (13):2108-15 Increased BCR responsiveness in B cells from patients with chronic GVHD.
Baker JV et al. AIDS 2014; 28 (6):831-40 Immunologic predictors of coronary artery calcium progression in a contemporary HIV cohort.
Cartwright EK et al. J Immunol 2014; 192 (10):4666-73 Divergent CD4+ T memory stem cell dynamics in pathogenic and nonpathogenic simian immunodeficiency virus infections.
Freeman CM et al. PLoS One 2014; 9 (5):e96421 Basal gene expression by lung CD4+ T cells in chronic obstructive pulmonary disease identifies independent molecular correlates of airflow obstruction and emphysema extent.
Wilson EM et al. J Infect Dis 2014; 210 (9):1396-406 Monocyte-activation phenotypes are associated with biomarkers of inflammation and coagulation in chronic HIV infection.
Werner-Klein M et al. PLoS One 2014; 9 (5):e97860 Immune humanization of immunodeficient mice using diagnostic bone marrow aspirates from carcinoma patients.
Gasper MA et al. AIDS 2014; 28 (8):1115-24 Natural killer cell and T-cell subset distributions and activation influence susceptibility to perinatal HIV-1 infection.
Fisher JP et al. Clin Cancer Res 2014; 20 (22):5720-32 Neuroblastoma killing properties of Vδ2 and Vδ2-negative γδT cells following expansion by artificial antigen-presenting cells.
Workalemahu G et al. J Immunol 2014; 193 (2):708-21 Metabolic engineering of Salmonella vaccine bacteria to boost human Vγ2Vδ2 T cell immunity.
Latimer B et al. Hum Vaccin Immunother 2014; 10 (8):2357-65 Strong HCV NS3/4a, NS4b, NS5a, NS5b-specific cellular immune responses induced in Rhesus macaques by a novel HCV genotype 1a/1b consensus DNA vaccine.
Buggert M et al. PLoS Pathog 2014; 10 (7):e1004251 T-bet and Eomes are differentially linked to the exhausted phenotype of CD8+ T cells in HIV infection.
Li Z et al. PLoS One 2014; 9 (9):e106064 γδ T cells are involved in acute HIV infection and associated with AIDS progression.
Wallin EF et al. Blood 2014; 124 (17):2666-74 Human T-follicular helper and T-follicular regulatory cell maintenance is independent of germinal centers.
van der Waart AB et al. Blood 2014; 124 (23):3490-500 Inhibition of Akt signaling promotes the generation of superior tumor-reactive T cells for adoptive immunotherapy.
Frencher JT et al. J Leukoc Biol 2014; 96 (6):957-67 HMBPP-deficient Listeria mutant immunization alters pulmonary/systemic responses, effector functions, and memory polarization of Vγ2Vδ2 T cells.
Soriano-Sarabia N et al. J Virol 2014; 88 (24):14070-7 Quantitation of replication-competent HIV-1 in populations of resting CD4+ T cells.
Corsiero E et al. PLoS One 2014; 9 (12):e114575 Accumulation of self-reactive na?ve and memory B cell reveals sequential defects in B cell tolerance checkpoints in Sj?gren's syndrome.
DiLillo DJ et al. Leukemia 2013; 27 (1):170-82 Chronic lymphocytic leukemia and regulatory B cells share IL-10 competence and immunosuppressive function.
Na IK et al. Haematologica 2013; 98 (1):23-30 Rabbit antithymocyte globulin (thymoglobulin) impairs the thymic output of both conventional and regulatory CD4+ T cells after allogeneic hematopoietic stem cell transplantation in adult patients.
Terahara K et al. PLoS One 2013; 8 (1):e53495 Expansion of activated memory CD4+ T cells affects infectivity of CCR5-tropic HIV-1 in humanized NOD/SCID/JAK3null mice.
Perreau M et al. J Exp Med 2013; 210 (1):143-56 Follicular helper T cells serve as the major CD4 T cell compartment for HIV-1 infection, replication, and production.
DeKosky BJ et al. Nat Biotechnol 2013; 31 (2):166-9 High-throughput sequencing of the paired human immunoglobulin heavy and light chain repertoire.
Roetynck S et al. PLoS One 2013; 8 (1):e55195 Phenotypic and functional profiling of CD4 T cell compartment in distinct populations of healthy adults with different antigenic exposure.
Canary LA et al. J Immunol 2013; 190 (6):2959-65 Rate of AIDS progression is associated with gastrointestinal dysfunction in simian immunodeficiency virus-infected pigtail macaques.
Labuda LA et al. PLoS Negl Trop Dis 2013; 7 (3):e2094 Alterations in peripheral blood B cell subsets and dynamics of B cell responses during human schistosomiasis.
Cubas RA et al. Nat Med 2013; 19 (4):494-9 Inadequate T follicular cell help impairs B cell immunity during HIV infection.
Cairo C et al. Immunology 2013; 138 (4):346-60 Human cord blood γδ T cells expressing public Vγ2 chains dominate the response to bisphosphonate plus interleukin-15.
Feuth T et al. PLoS One 2013; 8 (3):e59302 Complementary role of HCV and HIV in T-cell activation and exhaustion in HIV/HCV coinfection.
Weiskopf D et al. Proc Natl Acad Sci U S A 2013; 110 (22):E2046-53 Comprehensive analysis of dengue virus-specific responses supports an HLA-linked protective role for CD8+ T cells.
Matthews K et al. PLoS One 2013; 8 (5):e63785 Clinical adjuvant combinations stimulate potent B-cell responses in vitro by activating dermal dendritic cells.
Danso-Abeam D et al. Orphanet J Rare Dis 2013; 8:79 Olmsted syndrome: exploration of the immunological phenotype.
Lee EM et al. Stem Cell Res Ther 2013; 4 (3):56 CD70-CD27 ligation between neural stem cells and CD4+ T cells induces Fas-FasL-mediated T-cell death.
Thedrez A et al. PLoS One 2013; 8 (5):e63322 A quantitative deficiency in peripheral blood Vγ9Vδ2 cells is a negative prognostic biomarker in ovarian cancer patients.
Santer DM et al. PLoS One 2013; 8 (6):e68308 Enhanced activation of memory, but not na?ve, B cells in chronic hepatitis C virus-infected patients with cryoglobulinemia and advanced liver fibrosis.
Mensen A et al. J Transl Med 2013; 11:188 Utilization of TREC and KREC quantification for the monitoring of early T- and B-cell neogenesis in adult patients after allogeneic hematopoietic stem cell transplantation.
Amos JD et al. J Virol 2013; 87 (20):11121-34 Lack of B cell dysfunction is associated with functional, gp120-dominant antibody responses in breast milk of simian immunodeficiency virus-infected African green monkeys.
Lee DH et al. J Neuroinflammation 2013; 10:123 Immunological and clinical consequences of splenectomy in a multiple sclerosis patient treated with natalizumab.
Xu X et al. PLoS One 2013; 8 (10):e77401 Changes of cytokines during a spaceflight analog--a 45-day head-down bed rest.
Li L et al. PLoS One 2013; 8 (12):e82196 Human CD8+ T cells from TB pleurisy respond to four immunodominant epitopes in Mtb CFP10 restricted by HLA-B alleles.
Zhou J et al. Cell Mol Immunol 2012; 9 (1):34-44 Anti-γδ TCR antibody-expanded γδ T cells: a better choice for the adoptive immunotherapy of lymphoid malignancies.
van der Vlugt LE et al. PLoS One 2012; 7 (2):e30883 Schistosomes induce regulatory features in human and mouse CD1d(hi) B cells: inhibition of allergic inflammation by IL-10 and regulatory T cells.
Ouwendijk WJ et al. J Neurovirol 2012; 18 (2):91-9 Simian varicella virus infection of Chinese rhesus macaques produces ganglionic infection in the absence of rash.
Kroenke MA et al. J Immunol 2012; 188 (8):3734-44 Bcl6 and Maf cooperate to instruct human follicular helper CD4 T cell differentiation.
Zompi S et al. PLoS Negl Trop Dis 2012; 6 (3):e1568 Dominant cross-reactive B cell response during secondary acute dengue virus infection in humans.
Boudov? S et al. J Infect Dis 2012; 205 (9):1448-55 Impact of persistent HIV replication on CD4 negative Vγ2Vδ2 T cells.
Portugal S et al. Malar J 2012; 11:162 B cell analysis of ethnic groups in Mali with differential susceptibility to malaria.
Hartigan-O'Connor DJ et al. Sci Transl Med 2012; 4 (136):136ra69 SIV replication in the infected rhesus macaque is limited by the size of the preexisting TH17 cell compartment.
Qi Y et al. PLoS One 2012; 7 (6):e39072 The acute environment, rather than T cell subset pre-commitment, regulates expression of the human T cell cytokine amphiregulin.
Pa?no T et al. Haematologica 2012; 97 (7):1110-4 CD20 positive cells are undetectable in the majority of multiple myeloma cell lines and are not associated with a cancer stem cell phenotype.
Kawano Y et al. Int J Oncol 2012; 41 (3):876-84 Multiple myeloma cells expressing low levels of CD138 have an immature phenotype and reduced sensitivity to lenalidomide.
Wege AK et al. PLoS Negl Trop Dis 2012; 6 (7):e1741 Leishmania major infection in humanized mice induces systemic infection and provokes a nonprotective human immune response.
de Vries RD et al. PLoS Pathog 2012; 8 (8):e1002885 Measles immune suppression: lessons from the macaque model.
Barbosa RR et al. Clin Exp Immunol 2012; 169 (3):263-72 Monocyte activation is a feature of common variable immunodeficiency irrespective of plasma lipopolysaccharide levels.
Perona-Wright G et al. Proc Natl Acad Sci U S A 2012; 109 (45):18535-40 Persistent loss of IL-27 responsiveness in CD8+ memory T cells abrogates IL-10 expression in a recall response.
Bj?rkstr?m NK et al. Blood 2012; 120 (17):3455-65 CD8 T cells express randomly selected KIRs with distinct specificities compared with NK cells.
Qiu Y et al. PLoS Pathog 2012; 8 (11):e1002984 Tim-3-expressing CD4+ and CD8+ T cells in human tuberculosis (TB) exhibit polarized effector memory phenotypes and stronger anti-TB effector functions.
Zha B et al. PLoS One 2012; 7 (11):e49835 Decrease in proportion of CD19+ CD24(hi) CD27+ B cells and impairment of their suppressive function in Graves' disease.
Demberg T et al. J Virol 2012; 86 (23):12591-604 Dynamics of memory B-cell populations in blood, lymph nodes, and bone marrow during antiretroviral therapy and envelope boosting in simian immunodeficiency virus SIVmac251-infected rhesus macaques.
2012; Vigorous response of human innate functioning IgM memory B cells upon infection by Neisseria gonorrhoeae.
2012; Leukocyte composition of human breast cancer.
Morita R et al. Immunity 2011; 34 (1):108-21 Human blood CXCR5(+)CD4(+) T cells are counterparts of T follicular cells and contain specific subsets that differentially support antibody secretion.
Iwata Y et al. Blood 2011; 117 (2):530-41 Characterization of a rare IL-10-competent B-cell subset in humans that parallels mouse regulatory B10 cells.
Libri V et al. Immunology 2011; 132 (3):326-39 Cytomegalovirus infection induces the accumulation of short-lived, multifunctional CD4+CD45RA+CD27+ T cells: the potential involvement of interleukin-7 in this process.
Brocca-Cofano E et al. Vaccine 2011; 29 (17):3310-9 Vaccine-elicited SIV and HIV envelope-specific IgA and IgG memory B cells in rhesus macaque peripheral blood correlate with functional antibody responses and reduced viremia.
Qu?ch TD et al. J Immunol 2011; 186 (8):4640-8 Anergic responses characterize a large fraction of human autoreactive naive B cells expressing low levels of surface IgM.
Huntington ND et al. Proc Natl Acad Sci U S A 2011; 108 (15):6217-22 IL-15 transpresentation promotes both human T-cell reconstitution and T-cell-dependent antibody responses in vivo.
Scheeren FA et al. PLoS One 2011; 6 (4):e17189 Antigen-specific monoclonal antibodies isolated from B cells expressing constitutively active STAT5.
Li L et al. PLoS One 2011; 6 (5):e20165 Identification of Mycobacterium tuberculosis-specific Th1, Th17 and Th22 cells using the expression of CD40L in tuberculous pleurisy.
Sagoo P et al. Sci Transl Med 2011; 3 (83):83ra42 Human regulatory T cells with alloantigen specificity are more potent inhibitors of alloimmune skin graft damage than polyclonal regulatory T cells.
Kling HM et al. Comp Med 2011; 61 (3):269-77 Alterations in peripheral blood B-cell populations in SHIV89.6P-infected macaques (Macacca fascicularis).
Tan X et al. J Virol 2011; 85 (16):8316-27 Retinoic acid as a vaccine adjuvant enhances CD8+ T cell response and mucosal protection from viral challenge.
Barbosa RR et al. PLoS One 2011; 6 (8):e22848 Primary B-cell deficiencies reveal a link between human IL-17-producing CD4 T-cell homeostasis and B-cell differentiation.
Kress AK et al. Viruses 2011; 3 (8):1439-59 Cell surface markers in HTLV-1 pathogenesis.
Li L et al. PLoS One 2011; 6 (8):e23700 Identification of M. tuberculosis-specific Th1 cells expressing CD69 generated in vivo in pleural fluid cells from patients with tuberculous pleurisy.
Hammerbeck CD et al. J Virol 2011; 85 (19):9929-44 T cells are not required for pathogenesis in the Syrian hamster model of hantavirus pulmonary syndrome.
Randall KL et al. J Exp Med 2011; 208 (11):2305-20 DOCK8 deficiency impairs CD8 T cell survival and function in humans and mice.
Klatt NR et al. Blood 2011; 118 (22):5803-12 SIV infection of rhesus macaques results in dysfunctional T- and B-cell responses to neo and recall Leishmania major vaccination.
Crawford TQ et al. J Virol 2011; 85 (23):12343-50 HIV-1 infection abrogates CD8+ T cell mitogen-activated protein kinase signaling responses.
Biswas S et al. Immunology 2011; 134 (4):419-33 Humoral immune responses in humanized BLT mice immunized with West Nile virus and HIV-1 envelope proteins are largely mediated via human CD5+ B cells.
Takamori A et al. Retrovirology 2011; 8:100 Functional impairment of Tax-specific but not cytomegalovirus-specific CD8+ T lymphocytes in a minor population of asymptomatic human T-cell leukemia virus type 1-carriers.
2011; Transgenic expression of human signal regulatory protein alpha in Rag2-/-gamma(c)-/- mice improves engraftment of human hematopoietic cells in humanized mice.
Freeman CM et al. J Immunol 2010; 184 (11):6504-13 Cytotoxic potential of lung CD8(+) T cells increases with chronic obstructive pulmonary disease severity and with in vitro stimulation by IL-18 or IL-15.
Ness-Schwickerath KJ et al. J Immunol 2010; 184 (12):7268-80 Cytokine requirements for the differentiation and expansion of IL-17A- and IL-22-producing human Vgamma2Vdelta2 T cells.
Zuo J et al. AIDS Res Hum Retroviruses 2010; 26 (6):681-4 Short communication: enhanced CD8+ T cell apoptosis in HIV-infected adolescents with virologic failure on protease inhibitor-based therapy.
Cairo C et al. Hum Immunol 2010; 71 (10):968-75 Impact of age, gender, and race on circulating γδ T cells.
Chen Z et al. Stem Cell Res 2010; 5 (3):212-25 Prospective isolation of clonogenic mantle cell lymphoma-initiating cells.
Burt TD et al. J Immunol 2010; 185 (9):5279-88 Naive human T cells are activated and proliferate in response to the heme oxygenase-1 inhibitor tin mesoporphyrin.
Ali Z et al. J Immunol 2009; 183 (8):5407-17 Gammadelta T cell immune manipulation during chronic phase of simian-human immunodeficiency virus infection [corrected] confers immunological benefits.
2007; Prolonged (E)-4-hydroxy-3-methyl-but-2-enyl pyrophosphate-driven antimicrobial and cytotoxic responses of pulmonary and systemic Vgamma2Vdelta2 T cells in macaques.
SDS
Sodium Azide.pdf
Package List Price ($)
$ 209