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CD276 antibody [MIH42] (PE)

Anti-CD276 antibody [MIH42] (PE) used in Flow cytometry (FACS). GTX43126

Cat No. GTX43126

Host Mouse
Clonality Monoclonal
Clone Name MIH42
Isotype IgG1
Application FACS
Reactivity Human
Package
100 test ($339)
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
FACS Assay dependent
Not tested in other applications.

Calculated MW

57 kDa. ( Note )

Specificity/Sensitivity

This antibody detects CD276, a member of the B7 family of co-stimulatory molecules also known as B7-H3.
PROPERTIES

Form

Liquid

Buffer

PBS, 0.09% Sodium Azide, 1% BSA, 5% Sucrose

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE. Protect from light.

Antigen Species

Human

Purification

Protein G purified
From tissue culture supernatant

Conjugation

Phycoerythrin (PE)

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Cd276 Molecule,4Ig-B7-H3,B7-H3,B7H3,B7Rp-2,Cd276

Background

The protein encoded by this gene belongs to the immunoglobulin superfamily, and thought to participate in the regulation of T-cell-mediated immune response. Studies show that while the transcript of this gene is ubiquitously expressed in normal tissues and solid tumors, the protein is preferentially expressed only in tumor tissues. Additionally, it was observed that the 3' UTR of this transcript contains a target site for miR29 microRNA, and there is an inverse correlation between the expression of this protein and miR29 levels, suggesting regulation of expression of this gene product by miR29. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]

Database

Research Area

DATA IMAGES
Anti-CD276 antibody [MIH42] (PE) used in Flow cytometry (FACS). GTX43126

GTX43126 FACS Image

FACS analysis of human peripheral blood monocytes using GTX43126 CD276 antibody [MIH42] (PE).

REFERENCE
REVIEW
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Package List Price ($)
$ 339