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CD276 antibody

Anti-CD276 antibody used in IHC (Paraffin sections) (IHC-P). GTX34211
Anti-CD276 antibody used in IHC (Paraffin sections) (IHC-P). GTX34211
Anti-CD276 antibody used in IHC (Paraffin sections) (IHC-P). GTX34211
Anti-CD276 antibody used in Western Blot (WB). GTX34211
Anti-CD276 antibody used in IHC (Paraffin sections) (IHC-P). GTX34211

Cat No. GTX34211

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, IHC-P, ELISA
Reactivity Human, Mouse, Rat
Package
100 μl ($319)
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB Assay dependent
IHC-P Assay dependent
ELISA Assay dependent
Not tested in other applications.

Calculated MW

57 kDa. ( Note )

Specificity/Sensitivity

CD276 Polyclonal Antibody detects endogenous levels of CD276 protein.
PROPERTIES

Form

Liquid

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Synthesized peptide derived from the Internal region of human CD276.

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Cd276 Molecule , 4Ig-B7-H3 , B7-H3 , B7H3 , B7Rp-2 , Cd276

Background

The protein encoded by this gene belongs to the immunoglobulin superfamily, and thought to participate in the regulation of T-cell-mediated immune response. Studies show that while the transcript of this gene is ubiquitously expressed in normal tissues and solid tumors, the protein is preferentially expressed only in tumor tissues. Additionally, it was observed that the 3' UTR of this transcript contains a target site for miR29 microRNA, and there is an inverse correlation between the expression of this protein and miR29 levels, suggesting regulation of expression of this gene product by miR29. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]

Database

Research Area

DATA IMAGES
Anti-CD276 antibody used in IHC (Paraffin sections) (IHC-P). GTX34211

GTX34211 IHC-P Image

Immunohistochemistry (IHC) analysis of paraffin-embedded Human Liver, antibody was diluted at 1:100.

Anti-CD276 antibody used in IHC (Paraffin sections) (IHC-P). GTX34211

GTX34211 IHC-P Image

Immunohistochemistry (IHC) analysis of paraffin-embedded Mouse Liver, antibody was diluted at 1:100.

Anti-CD276 antibody used in IHC (Paraffin sections) (IHC-P). GTX34211

GTX34211 IHC-P Image

Immunohistochemistry (IHC) analysis of paraffin-embedded Mouse Liver, antibody was diluted at 1:100.

Anti-CD276 antibody used in Western Blot (WB). GTX34211

GTX34211 WB Image

Western Blot (WB) analysis of 293 cells using CD276 Polyclonal Antibody.

Anti-CD276 antibody used in IHC (Paraffin sections) (IHC-P). GTX34211

GTX34211 IHC-P Image

Immunohistochemistry (IHC) analysis of paraffin-embedded Human Liver, antibody was diluted at 1:100.

REFERENCE
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Package List Price ($)
$ 319