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CD3 antibody [PS1] (ready-to-use)

Anti-CD3 antibody [PS1] (ready-to-use) used in IHC (Paraffin sections) (IHC-P). GTX73504
Anti-CD3 antibody [PS1] (ready-to-use) used in IHC (Paraffin sections) (IHC-P). GTX73504

Cat No. GTX73504

Host

Mouse

Clonality

Monoclonal

Clone Name

PS1

Isotype

IgG2a

Application

IHC-P, IHC-Fr

Reactivity

Human
Package
6 ml ($299)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
IHC-P Assay dependent
IHC-Fr Assay dependent
Not tested in other applications.

Calculated MW

19 kDa. ( Note )

Specificity/Sensitivity

Epsilon chain of the CD3 complex. This antibody is a pan T cell marker. On the lymphocyte surface, this antibody binds to 22/26/30 kD molecule, which is associated with T cell antigen receptor complex. This antibody reacts with T cell chronic lymphocytic leukemias as well as with acute lymphoblastic leukemias of T cell origin.

PROPERTIES

Form

Liquid

Buffer

PBS with <0.1% sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Epsilon Chain of CD3.

Purification

Purified IgG

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

CD3D , CD3DELTA , CD3d molecule , IMD19 , T3D , CD3 delta

Cellular Localization

Membrane

Background

The protein encoded by this gene is part of the T-cell receptor/CD3 complex (TCR/CD3 complex) and is involved in T-cell development and signal transduction. The encoded membrane protein represents the delta subunit of the CD3 complex, and along with four other CD3 subunits, binds either TCR alpha/beta or TCR gamma/delta to form the TCR/CD3 complex on the surface of T-cells. Defects in this gene are a cause of severe combined immunodeficiency autosomal recessive T-cell-negative/B-cell-positive/NK-cell-positive (SCIDBNK). Two transcript variants encoding different isoforms have been found for this gene. Other variants may also exist, but the full-length natures of their transcripts has yet to be defined. [provided by RefSeq, Feb 2009]

Database

Research Area

DATA IMAGES

Anti-CD3 antibody [PS1] (ready-to-use) used in IHC (Paraffin sections) (IHC-P). GTX73504

GTX73504 IHC-P Image

Formalin fixed paraffin embedded human tonsil stained with CD3 antibody (cat. # GTX20828).

Anti-CD3 antibody [PS1] (ready-to-use) used in IHC (Paraffin sections) (IHC-P). GTX73504

GTX73504 IHC-P Image

IHC-P analysis of human tonsil using CD3 antibody [PS1].

REFERENCE

REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 299