For IHC-P: Use at a dilution of 1:100. Antigen retrieval is suggested by boiling tissue sections in 10mM citrate buffer, pH 6.0 for 10 min followed by cooling at room temperature for 20 min.
This antibody is suitable for staining normal and neoplastic T cells in formalin-fixed, paraffin-embedded tissues.
TCS containing 0.1% sodium azide
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.
Tissue Culture Supernatant
Synthetic peptide: KAKAKPVTRGAGA, corresponding to amino acids 156-168 of Human CD3 epsilon chain.
From hybridoma culture supernatant
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
T3E, 186740, P09693, T3D, 916, CD3-GAMMA, 917, CD3GAMMA, TCRE, P20963, 186830, 186780, P04234, CD3ZETA, CD3H, CD3Q, CD3E, CD3, CD3-DELTA, TCRZ, 919, CD3Z, CD3G, 915, CD3-ZETA, 186790, T3G, CD3D, P07766, CD3DELTA, CD3 ZETA, CD3 GAMMA, CD3 DELTA
Type I membrane protein.
The protein encoded by this gene is part of the T-cell receptor/CD3 complex (TCR/CD3 complex) and is involved in T-cell development and signal transduction. The encoded membrane protein represents the delta subunit of the CD3 complex, and along with four other CD3 subunits, binds either TCR alpha/beta or TCR gamma/delta to form the TCR/CD3 complex on the surface of T-cells. Defects in this gene are a cause of severe combined immunodeficiency autosomal recessive T-cell-negative/B-cell-positive/NK-cell-positive (SCIDBNK). Two transcript variants encoding different isoforms have been found for this gene. Other variants may also exist, but the full-length natures of their transcripts has yet to be defined. [provided by RefSeq]