GeneTex
United States (US)

CD3 delta antibody

GTX105811_40821_WB_19011506_407.jpg

Cat No. GTX105811

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB
Reactivity Human
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:5000-1:20000
Not tested in other applications.

Calculated MW

19 kDa. ( Note )

Positive Control

Jurkat membrane
PROPERTIES

Form

Liquid

Buffer

1XPBS, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1mg/ml(Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant protein encompassing a sequence within the center region of human CD3 delta. The exact sequence is proprietary.

Purification

Purified by antigen-affinity chromatography.

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

CD3-DELTA antibody, T3D antibody, CD3D antibody, T-cell receptor T3 delta chain antibody, "CD3d antigen, delta polypeptide (TiT3 complex) antibody", "CD3 antigen, delta subunit antibody", T-cell surface glycoprotein CD3 delta chain antibody, "OKT3, delta chain antibody", "CD3d molecule, delta (CD3-TCR complex) antibody"

Cellular Localization

Membrane

Background

The protein encoded by this gene is part of the T-cell receptor/CD3 complex (TCR/CD3 complex) and is involved in T-cell development and signal transduction. The encoded membrane protein represents the delta subunit of the CD3 complex, and along with four other CD3 subunits, binds either TCR alpha/beta or TCR gamma/delta to form the TCR/CD3 complex on the surface of T-cells. Defects in this gene are a cause of severe combined immunodeficiency autosomal recessive T-cell-negative/B-cell-positive/NK-cell-positive (SCIDBNK). Two transcript variants encoding different isoforms have been found for this gene. Other variants may also exist, but the full-length natures of their transcripts has yet to be defined. [provided by RefSeq]

Database

Research Area

DATA IMAGES
GTX105811_40821_WB_19011506_407.jpg

GTX105811 WB Image

Sample (30 ug of whole cell lysate)
A: Jurkat membrane
12% SDS PAGE
GTX105811 diluted at 1:10000

SDS
PBS.pdf
Glycerol.pdf
Thimerosal.pdf
Package List Price ($)
$ 319
$ 169