GeneTex
United States (US)

CD3 epsilon antibody [145-2C11] (FITC)

CD3e-antibody-145-2C11-FITC_FACS_GTX16182-1_18121409_848.jpg
CD3e-antibody-145-2C11-FITC_FACS_GTX16182-2_18121409_660.jpg

Cat No. GTX16182

Host Hamster
Clonality Monoclonal
Clone Name 145-2C11
Isotype IgG
Application FACS
Reactivity Mouse
APPLICATION

Application Note

For FACS: Use 0.5 ug to label 10^6 cells. Protocols are available upon request.

Calculated MW

21 kDa. ( Note )

Specificity/Sensitivity

Mouse CD3E
PROPERTIES

Form

Liquid

Buffer

Phosphate buffered saline containing 0.02% sodium azide and BSA

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. Protect from light.

Concentration

0.1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Mouse

Immunogen

Tissue / cell preparation, H-2Kb-specific mouse cytotoxic T lymphocyte clone BM10-37.

Purification

Purified Ig

Conjugation

Fluorescein isothiocyanate (FITC)

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Cd3 Antigen, Epsilon Polypeptide,Ai504783,Cd3,Cd3Epsilon,T3E,Cd3E

Cellular Localization

Cell Membrane

Background

T cell activation through the antigen receptor (TCR) involves the cytoplasmic tails of the CD3 subunits CD3 gamma, CD3 delta, CD3 epsilon and CD3 zeta. These CD3 subunits are structurally related members of the immunoglobulins super family encoded by closely linked genes on human chromosome 11. The CD3 components have long cytoplasmic tails that associate with cytoplasmic signal transduction molecules. This association is mediated at least in part by a double tyrosine-based motif present in a single copy in the CD3 subunits. CD3 may play a role in TCR-induced growth arrest, cell survival and proliferation.

Database

Research Area

DATA IMAGES
CD3e-antibody-145-2C11-FITC_FACS_GTX16182-1_18121409_848.jpg

GTX16182 FACS Image

Staining of thymocytes using CD3e: FITC antibody (GTX16182) and FITC hamster IgG isotype control

CD3e-antibody-145-2C11-FITC_FACS_GTX16182-2_18121409_660.jpg

GTX16182 FACS Image

Staining of splenic T cells using CD3e: FITC antibody (GTX16182) and FITC hamster IgG isotype control

Package List Price ($)
$ 289