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CD3 epsilon antibody [C3e/2858R]

Anti-CD3 epsilon antibody [C3e/2858R] used in Western Blot (WB). GTX02604
Anti-CD3 epsilon antibody [C3e/2858R] used in IHC (Paraffin sections) (IHC-P). GTX02604

Cat. No. GTX02604

Host

 Rabbit

Clonality

 Monoclonal

Clone Name

 C3e/2858R

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Human
Package
100 μg ($529)
See all CD3 epsilon products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1-2 μg/ml
IHC-P 1-2 μg/ml

Note :

IHC-P
Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris buffer with 1mM EDTA (pH 9.0) for 45 min at 95ºC followed by cooling at RT for 20 minutes.
Not tested in other applications.

Calculated MW

23 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 0.05% BSA

Preservative

0.05% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.

Concentration

200 μg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant human CD3e fragment (aa 23-119)

Purification

Protein A/G purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

CD3e molecule , IMD18 , T3E , TCRE

Cellular Localization

Cell membrane

Background

The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-CD3 epsilon antibody [C3e/2858R] used in Western Blot (WB). GTX02604

GTX02604 WB Image

WB analysis of Jurkat whole cell lysate using GTX02604 CD3 epsilon antibody [C3e/2858R].

Anti-CD3 epsilon antibody [C3e/2858R] used in IHC (Paraffin sections) (IHC-P). GTX02604

GTX02604 IHC-P Image

IHC-P analysis of human lymph Node tissue section using GTX02604 CD3 epsilon antibody [C3e/2858R].

REFERENCE

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REVIEW

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Package List Price ($)
$ 529