GeneTex
  • Country / Location Selection

United States (US)

CD3 epsilon antibody [UCHT1] (APC)

Anti-CD3 epsilon antibody [UCHT1] (APC) used in Flow cytometry (FACS). GTX76164

Cat No. GTX76164

Host

Mouse

Clonality

Monoclonal

Clone Name

UCHT1

Isotype

IgG1

Application

FACS

Reactivity

Human, Chimpanzee
Package
50 test ($319)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
FACS Neat

Note :

FACS
Use 10μl of the suggested working dilution to label 106 cells or 100μl whole blood.

Not tested in other applications.

Specificity/Sensitivity

This antibody binds to a region in the ectodomain of human CD3ε and has been shown to bind to a discontinuous epitope near an acidic region of CD3ε opposite the dimer interface.

PROPERTIES

Form

Liquid

Buffer

PBS, 0.09% Sodium Azide, 1% BSA, 5% Sucrose

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE. Protect from light.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Human infant thymocytes and lymphocytes from a patient with Sezary Syndrome.

Purification

Protein G purified
From tissue culture supernatant

Conjugation

Allophycocyanin (APC)

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

T3E Antibody , TCRE Antibody , CD3e molecule, epsilon (CD3-TCR complex) Antibody , CD3E Antibody

Background

The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. [provided by RefSeq, Jul 2008]

Research Area

DATA IMAGES

Anti-CD3 epsilon antibody [UCHT1] (APC) used in Flow cytometry (FACS). GTX76164

GTX76164 FACS Image

Figure A. RPE conjugated Mouse anti Human CD46 (GTX75835) and APC conjugated Mouse IgG1 isotype control (GTX76634). Figure B. RPE conjugated Mouse anti Human CD46 (GTX75835) and APC conjugated Mouse anti Human CD3 (GTX76164). All experiments performed on human Peripheral blood lymphocytes

REFERENCE

There are currently no references for CD3 epsilon antibody [UCHT1] (APC) (GTX76164). Be the first to share your publications with this product.

REVIEW

There are currently no reviews for CD3 epsilon antibody [UCHT1] (APC) (GTX76164). Be the first to share your experience with this product.
SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 319