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CD3 epsilon antibody [UCHT1] (PE-Cy5)

Cat. No. GTX00598-09

Reference 1

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 UCHT1

Isotype

 IgG1

Application

 FACS

Reactivity

 Human, Primate
Package
100 test ($359)
See all CD3 epsilon products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
FACS 4 μl reagent / 100 μl of whole blood or 10⁶ cells in a suspension
Not tested in other applications.

Calculated MW

23 kDa. ( Note )

Product Note

This antibody reacts with the epsilon chain of the CD3 complex.

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

15mM Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE. Protect from light.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

human thymocytes followed by Sezary T cells

Purification

Purified by size-exclusion chromatography

Conjugation

Phycoerythrin-Cyanine5 (PE-Cy5)

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption. Cy and CyDye are trademarks of GE Healthcare.

TARGET

Synonyms

CD3E , CD3e molecule , IMD18 , T3E , TCRE , CD3 epsilon

Cellular Localization

Membrane

Background

The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. [provided by RefSeq, Jul 2008]

Database

Research Area

REFERENCE

Clone Reference

Yarbrough WM et al. Circulation 2003; 108 (14):1753-9 Selective targeting and timing of matrix metalloproteinase inhibition in post-myocardial infarction remodeling.
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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 359