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CD3 epsilon antibody [UCHT1]

Cat No. GTX00598

Host

Mouse

Clonality

Monoclonal

Clone Name

UCHT1

Isotype

IgG1

Application

IHC-Fr, FACS, IP, MS

Reactivity

Human, Primate
Package
100 μg ($319)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
IHC-Fr Assay dependent
FACS Assay dependent
IP Assay dependent
MS Assay dependent
Not tested in other applications.

Calculated MW

23 kDa. ( Note )

Specificity/Sensitivity

This antibody reacts with the epsilon chain of the CD3 complex.

PROPERTIES

Form

Liquid

Buffer

PBS, 15mM sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

human thymocytes followed by Sezary T cells

Purification

Protein A purified

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

CD3E,CD3e molecule,IMD18,T3E,TCRE,CD3 epsilon

Cellular Localization

Membrane

Background

The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. [provided by RefSeq, Jul 2008]

Database

Research Area

REFERENCE

There are currently no references for CD3 epsilon antibody [UCHT1] (GTX00598). Be the first to share your publications with this product.

REVIEW

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