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CD30 antibody

Anti-CD30 antibody used in IHC (Paraffin sections) (IHC-P). GTX34482

Cat No. GTX34482

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

IHC-P

Reactivity

Human
Package
100 μg ($339)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
IHC-P 1-2μg/ml for 30 minutes at RT

Note :

IHC-P
Staining of formalin-fixed tissues require heating tissue sections in 10mM Tris buffer with 1mM EDTA, pH 8.0, for 45 min at 95ºC followed by cooling at RT for 20 minutes.

Not tested in other applications.

Calculated MW

64 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

10mM PBS, 0.05% BSA, 0.05% sodium azide (Please contact us for PBS only format)

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.2 mg/ml

Antigen Species

Human

Immunogen

Recombinant human TNFRSF8 protein fragment

Purification

Protein A purified

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

CD30,D1S166E,Ki1,TNF receptor superfamily member 8,TNFRSF8

Cellular Localization

Cell membrane,Cytoplasm

Background

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB. This receptor is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]

Database

  • Gene ID: 943 TNFRSF8
  • UniProt: P28908 TNFRSF8

Research Area

DATA IMAGES

Anti-CD30 antibody used in IHC (Paraffin sections) (IHC-P). GTX34482

GTX34482 IHC-P Image

IHC-P analysis of human Hodgkin's lymphoma tissue using GTX34482 CD30 antibody.

REFERENCE

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REVIEW

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Package List Price ($)
$ 339