GeneTex

  • Country / Location Selection

United States (US)

CD32 antibody [IV.3]

Cat. No. GTX14572

Reference 4

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 IV.3

Isotype

 IgG2b

Application

 FACS, ELISA, Neutralizing/Inhibition

Reactivity

 Human
Package
250 μg ($399)
See all CD32 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
FACS Assay dependent
ELISA Assay dependent
Neutralizing/Inhibition Assay dependent

Note :

Neutralizing/Inhibition
in vivo FcγRIIA blockade in humanized mice ; in vitro FcγRIIA blockade
Not tested in other applications.

Calculated MW

35 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

Filter-sterilized PBS

Preservative

No preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Human K562 leukemia cell line

Purification

Protein G purified
From tissue culture supernatant

Purity

>95% (Determined by SDS-PAGE)

Endotoxin

< 0.002 EU/弮g (Determined by LAL assay)

Conjugation

Unconjugated

RRID

AB_2887518

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

CD32,CD32A,CDw32,FCG2,FCGR2,FCGR2A,FCGR2A1,Fc fragment of IgG receptor IIa,FcGR,IGFR2

Cellular Localization

Cell membrane

Background

This gene encodes one member of a family of immunoglobulin Fc receptor genes found on the surface of many immune response cells. The protein encoded by this gene is a cell surface receptor found on phagocytic cells such as macrophages and neutrophils, and is involved in the process of phagocytosis and clearing of immune complexes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2008]

Database

Research Area

REFERENCE

Application Reference

Y Ye et al. Platelets 2024; 35 (1) : 2308635 Antiplatelet effects of the CEACAM1-derived peptide QDTT
Yun-Jong Park et al. PLoS Pathog 2022; 18 (4) : e1010468 D-dimer and CoV-2 spike-immune complexes contribute to the production of PGE2 and proinflammatory cytokines in monocytes.
Application : Neutralizing/Inhibition
Reactivity : Human
Duan R et al. Int J Mol Sci 2021; 23 (1) Spontaneous Platelet Aggregation in Blood Is Mediated by FcγRIIA Stimulation of Bruton's Tyrosine Kinase.
Li M et al. PLoS One 2018; 13 (7) : e0200478 Dengue immune sera enhance Zika virus infection in human peripheral blood monocytes through Fc gamma receptors.
Submit a Reference

REVIEW

There are currently no reviews for CD32 antibody [IV.3] (GTX14572). Be the first to share your experience with this product.
Submit a Review
Package List Price ($)
$ 399