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CD33 antibody [WM53]

Anti-CD33 antibody [WM53] used in Flow cytometry (FACS). GTX00477

Cat No. GTX00477

Host

Mouse

Clonality

Monoclonal

Clone Name

WM53

Isotype

IgG1

Application

WB, ICC/IF, IHC-Fr, FACS, IP, MS

Reactivity

Human, Primate
Package
100 μg ($319)
PRODUCT

Summary

CD33, also known as Siglec-3 or gp67, is a 67 kDa glycosylated cell surface receptor that mediates cell-cell interactions and maintains immune cells in a resting state. Although CD33 is found on some lymphoid subsets, it is highly expressed on myeloid lineage cells, and is commonly used for the diagnosis of acute myeloid leukemia (AML). CD33 is an established target for therapy, with CD33-positive blasts detected in almost 90 percent of patients presenting with AML.

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB Assay dependent
ICC/IF Assay dependent
IHC-Fr Assay dependent
FACS Assay dependent
IP Assay dependent
MS Assay dependent
Not tested in other applications.

Calculated MW

40 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 15mM sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Human AML cells

Purification

Protein A purified

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

CD33 , CD33 molecule , SIGLEC3 , p67

Cellular Localization

Cell membrane

Database

Research Area

DATA IMAGES

Anti-CD33 antibody [WM53] used in Flow cytometry (FACS). GTX00477

GTX00477 FACS Image

FACS analysis of human peripheral blood using GTX00477 CD33 antibody [WM53].

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf