GeneTex
  • Country / Location Selection

United States (US)

CD36 antibody [FA6.152]

Cat No. GTX44214

Host

Mouse

Clonality

Monoclonal

Clone Name

FA6.152

Isotype

IgG1

Application

FACS, IHC

Reactivity

Human
Package
100 μg ($359)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
FACS 2 μg
IHC Assay dependent

Note :

FACS
5x10⁵ cells/test

Not tested in other applications.

Calculated MW

53 kDa. ( Note )

Product Note

The molecular weight of the recognized antigen is 90 kDa. Recognizes the glycoprotein gp lllbcorresponding to the thrombospondin receptor. This antibody agglutinates fetal but not adult erythrocytes. Itdoes not react with lymphocytes and granulocytes. It reacts both with fetal and adult monocytes,megakaryocytes, platelets and reticulocytes. The thrombospondin receptor is a very early marker oferythroid differentiation.

PROPERTIES

Form

Liquid

Buffer

PBS, 1mg/ml BSA

Preservative

No preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.20 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

20 week-old human fetal red blood cells.

Purification

Purified IgG

Conjugation

Unconjugated

RRID

AB_11165682

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

CD36 molecule , BDPLT10 , CHDS7 , FAT , GP3B , GP4 , GPIV , PASIV , SCARB3

Cellular Localization

Cell membrane , Golgi apparatus , Apical cell membrane

Background

The protein encoded by this gene is the fourth major glycoprotein of the platelet surface and serves as a receptor for thrombospondin in platelets and various cell lines. Since thrombospondins are widely distributed proteins involved in a variety of adhesive processes, this protein may have important functions as a cell adhesion molecule. It binds to collagen, thrombospondin, anionic phospholipids and oxidized LDL. It directly mediates cytoadherence of Plasmodium falciparum parasitized erythrocytes and it binds long chain fatty acids and may function in the transport and/or as a regulator of fatty acid transport. Mutations in this gene cause platelet glycoprotein deficiency. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Feb 2014]

Database

Research Area

REFERENCE

REVIEW

There are currently no reviews for CD36 antibody [FA6.152] (GTX44214). Be the first to share your experience with this product.
SDS
PBS.pdf
Package List Price ($)
$ 359