GeneTex
United States (US)

CD36 antibody [VM58]

img18160_18121411_587.jpg

Cat No. GTX28140

Host Mouse
Clonality Monoclonal
Clone Name VM58
Isotype IgG1
Application ICC/IF, IHC-Fr, IHC
Reactivity Human
APPLICATION

Calculated MW

53 kDa. ( Note )

Specificity/Sensitivity

The monoclonal antibody VM58 is directed against the CD36 antigen, a 90kD glycoprotein, also called GP IIIb expressed on human platelets. The GP IV (GP IIIb) molecule has been shown to function as thrombospondin receptor on platelets and monocytes and as receptor for Plasmodium falciparum infected erythrocytes. The monoclonal antibody reacts with platelets, monocytes, macrophages, erythroblasts and (weakly) with B-cells. In immunohistology the monoclonal antibody reacts with some endothelial cells, adipocytes and the granular layer of the skin. The antibody VM58 induces Fc-receptor-dependent platelet aggregation after binding to platelet. The heterogeneity of the response found in healthy individuals is dependent on the polymorphism of the Fc RII on platelets.
PROPERTIES

Form

Liquid

Buffer

PBS with approximately 0.2 mg antibody/ml and sodium azide.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.2mg/ml(Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Human monocytes.

Purification

IgG fraction
Ammonium sulfate + DEAE-cellulose, gradient elution

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

GPIV, FAT, GP3B, 948, SCARB3, 173510, CD36, PASIV, P16671, GP4

Background

Functional studies on CD36.

Database

Research Area

DATA IMAGES
img18160_18121411_587.jpg

GTX28140 IHC Image


Package List Price ($)
$ 289