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CD38 antibody [CD38/4247R]

Anti-CD38 antibody [CD38/4247R] used in IHC (Paraffin sections) (IHC-P). GTX02603
Anti-CD38 antibody [CD38/4247R] used in Western Blot (WB). GTX02603
Anti-CD38 antibody [CD38/4247R] used in IHC (Paraffin sections) (IHC-P). GTX02603

Cat. No. GTX02603

Reference 1

Host

 Rabbit

Clonality

 Monoclonal

Clone Name

 CD38/4247R

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Human
Package
100 μg ($529)
See all CD38 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 2-4 μg/ml
IHC-P 1-2 μg/ml

Note :

IHC-P
Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris buffer with 1mM EDTA (pH 9.0) for 45 min at 95ºC followed by cooling at RT for 20 minutes.
Not tested in other applications.

Calculated MW

34 kDa. ( Note )

Observed MW

45 kDa. The observed M.W. is based on the following publication. PMID: 24319640

PROPERTIES

Form

Liquid

Buffer

10mM PBS, 0.05% BSA

Preservative

0.05% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.

Concentration

200 μg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Synthetic peptide corresponding to residues within aa200-300 of CD38

Purification

Protein A/G purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

CD38 molecule , ADPRC 1 , ADPRC1

Background

The protein encoded by this gene is a non-lineage-restricted, type II transmembrane glycoprotein that synthesizes and hydrolyzes cyclic adenosine 5'-diphosphate-ribose, an intracellular calcium ion mobilizing messenger. The release of soluble protein and the ability of membrane-bound protein to become internalized indicate both extracellular and intracellular functions for the protein. This protein has an N-terminal cytoplasmic tail, a single membrane-spanning domain, and a C-terminal extracellular region with four N-glycosylation sites. Crystal structure analysis demonstrates that the functional molecule is a dimer, with the central portion containing the catalytic site. It is used as a prognostic marker for patients with chronic lymphocytic leukemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]

Database

Research Area

DATA IMAGES

Anti-CD38 antibody [CD38/4247R] used in IHC (Paraffin sections) (IHC-P). GTX02603

GTX02603 IHC-P Image

IHC-P analysis of human tonsil tissue section using GTX02603 CD38 antibody [CD38/4247R].

Anti-CD38 antibody [CD38/4247R] used in Western Blot (WB). GTX02603

GTX02603 WB Image

WB analysis of Raji whole cell lysate using GTX02603 CD38 antibody [CD38/4247R].

Anti-CD38 antibody [CD38/4247R] used in IHC (Paraffin sections) (IHC-P). GTX02603

GTX02603 IHC-P Image

IHC-P analysis of human tonsil tissue section using GTX02603 CD38 antibody [CD38/4247R].

REFERENCE

Application Reference

Wang J et al. Antioxidants (Basel) 2021; 10 (2) Exogenous NAD+ Postpones the D-Gal-Induced Senescence of Bone Marrow-Derived Mesenchymal Stem Cells via Sirt1 Signaling.
Application : WB
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REVIEW

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Package List Price ($)
$ 529