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CD38 antibody [SPC32]

Anti-CD38 antibody [SPC32] used in IHC (Paraffin sections) (IHC-P). GTX01959

Cat. No. GTX01959

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 SPC32

Isotype

 IgG1

Application

 IHC-P

Reactivity

 Human
Package
500 μl ($519)
See all CD38 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-P 1:100

Note :

IHC-P
The recommended fixative is 10% neutral-buffered formalin for paraffin-embedded tissue sections. Heat Induced Epitope Retreival (HIER) was performed in Epitope Retreival Solution pH6.
Not tested in other applications.

Calculated MW

34 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

Tissue culture supernatant

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.

Antigen Species

Human

Immunogen

Prokaryotic recombinant fusion protein corresponding to the extracellular region of the CD38 molecule.

Purification

Unpurified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

CD38 molecule , ADPRC 1 , ADPRC1

Background

The protein encoded by this gene is a non-lineage-restricted, type II transmembrane glycoprotein that synthesizes and hydrolyzes cyclic adenosine 5'-diphosphate-ribose, an intracellular calcium ion mobilizing messenger. The release of soluble protein and the ability of membrane-bound protein to become internalized indicate both extracellular and intracellular functions for the protein. This protein has an N-terminal cytoplasmic tail, a single membrane-spanning domain, and a C-terminal extracellular region with four N-glycosylation sites. Crystal structure analysis demonstrates that the functional molecule is a dimer, with the central portion containing the catalytic site. It is used as a prognostic marker for patients with chronic lymphocytic leukemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]

Database

Research Area

DATA IMAGES

Anti-CD38 antibody [SPC32] used in IHC (Paraffin sections) (IHC-P). GTX01959

GTX01959 IHC-P Image

IHC-P analysis of chronically inflamed human bronchus tissue using GTX01959 CD38 antibody [SPC32]. Note intense membrane staining of infiltrating activated T lymphocytes.

REFERENCE

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REVIEW

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Package List Price ($)
$ 519